气候变化领域集成服务门户(CCPortal): Altered neurotransmitter function in CO2-exposed stickleback (Gasterosteus aculeatus): a temperate model species for ocean acidification research

CCPortal

DOI	https://doi.org/10.1594/PANGAEA.849392
	Altered neurotransmitter function in CO2-exposed stickleback (Gasterosteus aculeatus): a temperate model species for ocean acidification research
	Lai; Floriana; Jutfelt; Fredrik; Nilsson; Göran E
发布日期	2015-09-15
数据集类型	dataset
英文关键词	Animalia ; Behaviour ; Chordata ; Coast and continental shelf ; Containers and aquaria (20- 1000 L or &lt ; 1 m**2) ; Gasterosteus aculeatus ; Growth/Morphology ; Laboratory experiment ; Nekton ; North Atlantic ; Pelagos ; Single species ; Temperate
英文简介	Studies on the consequences of ocean acidification for the marine ecosystem have revealed behavioural changes in coral reef fishes exposed to sustained near-future CO2 levels. The changes have been linked to altered function of GABAergic neurotransmitter systems, because the behavioural alterations can be reversed rapidly by treatment with the GABAA receptor antagonist gabazine. Characterization of the molecular mechanisms involved would be greatly aided if these can be examined in a well-characterized model organism with a sequenced genome. It was recently shown that CO2-induced behavioural alterations are not confined to tropical species, but also affect the three-spined stickleback, although an involvement of the GABAA receptor was not examined. Here, we show that loss of lateralization in the stickleback can be restored rapidly and completely by gabazine treatment. This points towards a worrying universality of disturbed GABAA function after high-CO2 exposure in fishes from tropical to temperate marine habitats. Importantly, the stickleback is a model species with a sequenced and annotated genome, which greatly facilitates future studies on underlying molecular mechanisms.
空间范围	Latitude: 58.263020 * Longitude: 11.496920
语种	英语
国家	国际
学科大类	气候变化
学科子类	气候变化
文献类型	数据集
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/216968
推荐引用方式 GB/T 7714	Lai,Floriana,Jutfelt,et al. Altered neurotransmitter function in CO2-exposed stickleback (Gasterosteus aculeatus): a temperate model species for ocean acidification research.2015-09-15.https://doi.org/10.1594/PANGAEA.849392.