气候变化领域集成服务门户(CCPortal): Indirect effects of climate changes on cadmium bioavailability and biological effects in the Mediterranean mussel Mytilus galloprovincialis

CCPortal

DOI	https://doi.org/10.1594/PANGAEA.872084
	Indirect effects of climate changes on cadmium bioavailability and biological effects in the Mediterranean mussel Mytilus galloprovincialis
	Nardi; Alessandro; Mincarelli; Luana Fiorella; Benedetti; Maura; Fattorini; Daniele; d'Errico; Giuseppe; Regoli; Francesco
发布日期	2017-02-15
数据集类型	dataset
英文关键词	Animalia ; Benthic animals ; Benthos ; Bottles or small containers/Aquaria ( 20 L) ; Coast and continental shelf ; Inorganic toxins ; Laboratory experiment ; Mediterranean Sea ; Mollusca ; Mytilus galloprovincialis ; Single species ; Temperate ; Temperature
英文简介	Despite the great interest in the consequences of climate change on the physiological functioning of marine organisms, indirect and interactive effects of rising temperature and pCO2 on bioaccumulation and responsiveness to environmental pollutants are still poorly explored, particularly in terms of cellular mechanisms. According to future projections of temperature and pH/pCO2, this study investigated the main cellular pathways involved in metal detoxification and oxidative homeostasis in Mediterranean mussels, Mytilus galloprovincialis, exposed for 4 weeks to various combinations of two levels of pH/pCO2 (8.2/400 µatm and 7.4/3000 µatm), temperature (20 and 25 °C), and cadmium addition (0 and 20 µg/L). Bioaccumulation was increased in metal exposed organisms but it was not further modulated by different temperature and pH/pCO2 combinations. However, interactions between temperature, pH and cadmium had significant effects on induction of metallothioneins, responses of the antioxidant system and the onset of oxidative damages, which was tissue dependent. Multiple stressors increased metallothioneins concentrations in the digestive gland revealing different oxidative effects: while temperature and cadmium enhanced glutathione-dependent antioxidant protection and capability to neutralize peroxyl radicals, the metal increased the accumulation of lipid peroxidation products under acidified conditions. Gills did not reveal specific effects for different combinations of factors, but a general stress condition was observed in this tissue after various treatments. Significant variations of immune system were mainly caused by increased temperature and low pH, while co-exposure to acidification and cadmium enhanced metal genotoxicity and the onset of permanent DNA damage in haemocytes. Elaboration of the whole biomarker data in a cellular hazard index, corroborated the synergistic effects of temperature and acidification which increased the toxicological effects of cadmium. The overall results confirmed that climate change could influence ecotoxicological effects of environmental contaminants, highlighting the importance of a better knowledge of cellular mechanisms to understand and predict responsiveness of marine organisms to such multiple stressors.
空间范围	Latitude: 43.500000 * Longitude: 13.700000
时间范围	2014-06-01T00:00:00 - 2014-06-30T00:00:00
语种	英语
国家	国际
学科大类	气候变化
学科子类	气候变化
文献类型	数据集
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/216651
推荐引用方式 GB/T 7714	Nardi,Alessandro,Mincarelli,et al. Indirect effects of climate changes on cadmium bioavailability and biological effects in the Mediterranean mussel Mytilus galloprovincialis.2017-02-15.https://doi.org/10.1594/PANGAEA.872084.