气候变化领域集成服务门户(CCPortal): Seawater carbonate chemistry and immune function of the Pacific oyster against Vibrio splendidus challenge

CCPortal

DOI	https://doi.org/10.1594/PANGAEA.889437
	Seawater carbonate chemistry and immune function of the Pacific oyster against Vibrio splendidus challenge
	Cao; Ruiwen; Wang; Qing; Yang; Dinglong; Liu; Yongliang; Ran; Wen; Qu; Yi; Wu; Huifeng; Cong; Ming; Li; Fei; Ji; Chenglong; Zhao; Jianmin
发布日期	2018-05-02
数据集类型	dataset
英文关键词	Animalia ; Benthic animals ; Benthos ; Coast and continental shelf ; Containers and aquaria (20- 1000 L or &lt ; 1 m**2) ; Crassostrea gigas ; Immunology/Self-protection ; Laboratory experiment ; Mollusca ; North Pacific ; Other ; Single species ; Temperate
英文简介	Ocean acidification (OA) and pathogenic diseases pose a considerable threat to key species of marine ecosystem. However, few studies have investigated the combined impact of reduced seawater pH and pathogen challenge on the immune responses of marine invertebrates. In this study, Pacific oysters, Crassostrea gigas, were exposed to OA (~2000 ppm) for 28 days and then challenged with Vibrio splendidus for another 72 h. Hemocyte parameters showed that V. splendidus infection exacerbated the impaired oyster immune responses under OA exposure. An iTRAQ-based quantitative proteomic analysis revealed that C. gigas responded differently to OA stress and V. splendidus challenge, alone or in combination. Generally, OA appears to act via a generalized stress response by causing oxidative stress, which could lead to cellular injury and cause disruption to the cytoskeleton, protein turnover, immune responses and energy metabolism. V. splendidus challenge in oysters could suppress the immune system directly and lead to a disturbed cytoskeleton structure, increased protein turnover and energy metabolism suppression, without causing oxidative stress. The combined OA- and V. splendidus-treated oysters ultimately presented a similar, but stronger proteomic response pattern compared with OA treatment alone. Overall, the impaired oyster immune functions caused by OA exposure may have increased the risk of V. splendidus infection. These results have important implications for the impact of OA on disease outbreaks in marine invertebrates, which would have significant economic and ecological repercussions.
语种	英语
国家	国际
学科大类	气候变化
学科子类	气候变化
文献类型	数据集
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/216206
推荐引用方式 GB/T 7714	Cao,Ruiwen,Wang,et al. Seawater carbonate chemistry and immune function of the Pacific oyster against Vibrio splendidus challenge.2018-05-02.https://doi.org/10.1594/PANGAEA.889437.