气候变化领域集成服务门户(CCPortal): Inactivating SARS-CoV-2 by electrochemical oxidation

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DOI	10.1016/j.scib.2020.12.025
	Inactivating SARS-CoV-2 by electrochemical oxidation
	Tu Y.; Tang W.; Yu L.; Liu Z.; Liu Y.; Xia H.; Zhang H.; Chen S.; Wu J.; Cui X.; Zhang J.; Wang F.; Hu Y.; Deng D.
发表日期	2021
ISSN	20959273
起始页码	720
结束页码	726
卷号	66 期号:7
英文摘要	Fully inactivating SARS-CoV-2, the virus causing coronavirus disease 2019, is of key importance for interrupting virus transmission but is currently performed by using biologically or environmentally hazardous disinfectants. Herein, we report an eco-friendly and efficient electrochemical strategy for inactivating the SARS-CoV-2 using in-situ formed nickel oxide hydroxide as anode catalyst and sodium carbonate as electrolyte. At a voltage of 5 V, the SARS-CoV-2 viruses can be rapidly inactivated with disinfection efficiency reaching 95% in only 30 s and 99.99% in 5 min. Mass spectrometry analysis and theoretical calculations indicate that the reactive oxygen species generated on the anode can oxidize the peptide chains and induce cleavage of the peptide backbone of the receptor binding domain of the SARS-CoV-2 spike glycoprotein, and thereby disables the virus. This strategy provides a sustainable and highly efficient approach for the disinfection of the SARS-CoV-2 viruliferous aerosols and wastewater. © 2020 Science China Press
关键词	Electrochemical oxidation Reactive oxygen species Receptor binding domain SARS-CoV-2
英文关键词	Anodes; Biohazards; Disinfection; Electrochemical oxidation; Electrolytes; Mass spectrometry; Nickel oxide; Peptides; Sodium Carbonate; Sodium compounds; Viruses; Wastewater treatment; Anode catalysts; Disinfection efficiency; Mass spectrometry analysis; Nickel oxide hydroxides; Peptide backbones; Receptor-binding domains; Theoretical calculations; Virus transmission; Diseases
语种	英语
来源期刊	Science Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/207577
作者单位	State Key Laboratory of Catalysis, Collaborative Innovation Center of Chemistry for Energy Materials, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China; CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; University of Chinese Academy of Sciences, Beijing, 100049, China; College of Materials Science and Engineering, Zhengzhou University, Zhengzhou, 450001, China; Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China
推荐引用方式 GB/T 7714	Tu Y.,Tang W.,Yu L.,et al. Inactivating SARS-CoV-2 by electrochemical oxidation[J],2021,66(7).
APA	Tu Y..,Tang W..,Yu L..,Liu Z..,Liu Y..,...&Deng D..(2021).Inactivating SARS-CoV-2 by electrochemical oxidation.Science Bulletin,66(7).
MLA	Tu Y.,et al."Inactivating SARS-CoV-2 by electrochemical oxidation".Science Bulletin 66.7(2021).