气候变化领域集成服务门户(CCPortal): Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals

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DOI	10.1111/ele.13831
	Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals
	Chavhan Y.; Malusare S.; Dey S.
发表日期	2021
ISSN	1461023X
起始页码	1943
结束页码	1954
卷号	24 期号:9
英文摘要	Theoretical models of ecological specialisation commonly assume that adaptation to one environment leads to fitness reductions (costs) in others. However, experiments often fail to detect such costs. We addressed this conundrum using experimental evolution with Escherichia coli in several constant and fluctuating environments at multiple population sizes. We found that in fluctuating environments, smaller populations paid significant costs, but larger ones avoided them altogether. Contrastingly, in constant environments, larger populations paid more costs than the smaller ones. Overall, large population sizes and fluctuating environments led to cost avoidance only when present together. Mutational frequency distributions obtained from whole-genome whole-population sequencing revealed that the primary mechanism of cost avoidance was the enrichment of multiple beneficial mutations within the same lineage. Since the conditions revealed by our study for avoiding costs are widespread, it provides a novel explanation of the conundrum of why the costs expected in theory are rarely detected in experiments. © 2021 John Wiley & Sons Ltd.
关键词	costs of adaptation ecological specialisation experimental evolution fluctuating environments maladaptation mutation fixation mutation supply whole-genome whole-population sequencing
英文关键词	Escherichia coli
语种	英语
来源期刊	Ecology Letters
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/204352
作者单位	Indian Institute of Science Education and Research (IISER) Pune, Pune, Maharashtra, India; Gaia Doctoral School, Institut des sciences de l'évolution (ISEM), 1093-1317 Route de Mende, Montpellier, 34090, France
推荐引用方式 GB/T 7714	Chavhan Y.,Malusare S.,Dey S.. Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals[J],2021,24(9).
APA	Chavhan Y.,Malusare S.,&Dey S..(2021).Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals.Ecology Letters,24(9).
MLA	Chavhan Y.,et al."Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals".Ecology Letters 24.9(2021).