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| Understanding the impact of global change on animal-borne diseases | |
| 项目编号 | 360G-Wellcome-220179_Z_20_Z |
| Dr David Redding | |
| 项目主持机构 | University of Exeter |
| 开始日期 | 2020-11-16 |
| 结束日期 | 2025-11-15 |
| 英文摘要 | We know little about how future climate change, habitat destruction, human population increases and greater globalisation processes will impact human zoonotic diseases. Here, I investigate the use of dynamic, seasonal host population models to better predict the impact of real-time environmental change on disease-carrying host species, within a general systems-dynamics, disease framework. Specifically, I will combine a mathematical compartmental disease model with a host population ecology model, within a spatial and temporal Bayesian framework. Using this approach, I will first model Lassa Fever using climate and land-use observations, collaborating with the Nigerian government. I will then augment my model to account for animal movement patterns and vector species abundances, to examine arboviral disease spread in North America. Then, I will integrate these threads into a general, dynamic modelling framework for zoonotic diseases, which will contain both the newly developed components and my previously developed model of human movement and behaviour. Working with the World Health Organisation, I will create short- and long-term disease forecasts for a set of high priority zoonoses. Once validated against human case data, these mechanistic models can be used to test interventions and create future disease management plans that are robust to upcoming global change. |
| 学科分类 | 14 - 医学科学 |
| 资助机构 | UK-WellcomeTrust |
| 项目经费 | 679929 |
| 项目类型 | Sir Henry Dale Fellowship |
| 国家 | UK |
| 语种 | 英语 |
| 文献类型 | 项目 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/190933 |
| 推荐引用方式 GB/T 7714 | Dr David Redding.Understanding the impact of global change on animal-borne diseases.2020. |
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