气候变化领域集成服务门户(CCPortal): Bioavailable soil Pb minimized by in situ transformation to plumbojarosite

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DOI	10.1073/pnas.2020315117
	Bioavailable soil Pb minimized by in situ transformation to plumbojarosite
	Karna R.R.; Noerpel M.R.; Nelson C.; Elek B.; Herbin-Davis K.; Diamond G.; Bradham K.; Thomas D.J.; Scheckel K.G.
发表日期	2021
ISSN	00278424
卷号	118 期号:3
英文摘要	Exposure to lead (Pb) during early life has persistent adverse health effects. During childhood, ingestion of bioavailable Pb in contaminated soils can be a major route of Pb absorption. Remediation to alter physiochemical properties of soil-borne Pb can reduce Pb bioavailability. Our laboratory-based approach for soil Pb remediation uses addition of iron (Fe) sulfate and application of heat to promote formation of plumbojarosite (PLJ), a sparingly soluble Pb-Fe hydroxysulfate mineral. We treated two soils with anthropogenic Pb contamination and samples of clean topsoil spiked with various Pb compounds (i.e., carbonate, chloride, phosphate [P], or sulfate) to convert native Pb species to PLJ and used a mouse assay to assess relative bioavailability (RBA) of Pb in untreated (U) and remediated soils. Bone and blood Pb levels were significantly lower (P < 0.001, Student’s t test) in mice that consumed diets amended with remediated soils than with U soils. Estimated RBA for Pb in both remediated natural soils and Pb-mineral spiked soils were reduced by >90% relative to Pb RBA for U soils, which is substantially more effective than other soil amendments, including P. X-ray absorption spectroscopy showed that >90% of all Pb species in remediated soils were converted to PLJ, and ingested PLJ was not chemically transformed during gastrointestinal tract transit. Post treatment neutralization of soil pH did not affect PLJ stability, indicating the feasibility in field conditions. These results suggest that formation of PLJ in contaminated soils can reduce the RBA of Pb and minimize this medium’s role as a source of Pb exposure for young children. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Bioavailability; Lead; Plumbojarosite; Remediation; Speciation
语种	英语
scopus关键词	carbonic acid; chloride; lead; mineral; plumbojarosite; unclassified drug; animal experiment; animal tissue; Article; bioavailability; bone level; controlled study; dietary intake; ecosystem restoration; female; gastrointestinal transit; lead blood level; mouse; nonhuman; priority journal; soil; soil acidity; soil amendment; soil pollution; soil treatment; species; X ray absorption spectroscopy
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180952
作者单位	Bennett Aerospace, Inc., Engineer Research and Development Center, USACE, Vicksburg, MS 39183, United States; Center for Environmental Solutions and Emergency Response, United States Environmental Protection Agency, Office of Research and Development, Cincinnati, OH 45224, United States; BioGeoChem Scientific LLC, Austin, TX 78745, United States; Center for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC 27711, United States; SRC, Inc., North Syracuse, NY 13212, United States; Center for Environmental Measurement and Modeling, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, NC 27711, United States
推荐引用方式 GB/T 7714	Karna R.R.,Noerpel M.R.,Nelson C.,et al. Bioavailable soil Pb minimized by in situ transformation to plumbojarosite[J],2021,118(3).
APA	Karna R.R..,Noerpel M.R..,Nelson C..,Elek B..,Herbin-Davis K..,...&Scheckel K.G..(2021).Bioavailable soil Pb minimized by in situ transformation to plumbojarosite.Proceedings of the National Academy of Sciences of the United States of America,118(3).
MLA	Karna R.R.,et al."Bioavailable soil Pb minimized by in situ transformation to plumbojarosite".Proceedings of the National Academy of Sciences of the United States of America 118.3(2021).