气候变化领域集成服务门户(CCPortal): Invariant timescale hierarchy across the cortical somatosensory network

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DOI	10.1073/pnas.2021843118
	Invariant timescale hierarchy across the cortical somatosensory network
	Rossi-Pool R.; Zainos A.; Alvarez M.; Parra S.; Zizumbo J.; Romo R.
发表日期	2021
ISSN	00278424
卷号	118 期号:3
英文摘要	The ability of cortical networks to integrate information from different sources is essential for cognitive processes. On one hand, sensory areas exhibit fast dynamics often phase-locked to stimulation; on the other hand, frontal lobe areas with slow response latencies to stimuli must integrate and maintain information for longer periods. Thus, cortical areas may require different timescales depending on their functional role. Studying the cortical somatosensory network while monkeys discriminated between two vibrotactile stimulus patterns, we found that a hierarchical order could be established across cortical areas based on their intrinsic timescales. Further, even though subareas (areas 3b, 1, and 2) of the primary somatosensory (S1) cortex exhibit analogous firing rate responses, a clear differentiation was observed in their timescales. Importantly, we observed that this inherent timescale hierarchy was invariant between task contexts (demanding vs. nondemanding). Even if task context severely affected neural coding in cortical areas downstream to S1, their timescales remained unaffected. Moreover, we found that these time constants were invariant across neurons with different latencies or coding. Although neurons had completely different dynamics, they all exhibited comparable timescales within each cortical area. Our results suggest that this measure is demonstrative of an inherent characteristic of each cortical area, is not a dynamical feature of individual neurons, and does not depend on task demands. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Timescale hierarchy \| behaving monkeys \| somatosensory network \| inherent time constants \| primary somatosensory cortex
语种	英语
scopus关键词	animal experiment; article; brain cortex; controlled study; firing rate; Haplorhini; human; nonhuman; primary somatosensory cortex
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180949
作者单位	Instituto de Fisiología Celular–Neurociencias, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico; El Colegio Nacional, Mexico City, 06020, Mexico
推荐引用方式 GB/T 7714	Rossi-Pool R.,Zainos A.,Alvarez M.,et al. Invariant timescale hierarchy across the cortical somatosensory network[J],2021,118(3).
APA	Rossi-Pool R.,Zainos A.,Alvarez M.,Parra S.,Zizumbo J.,&Romo R..(2021).Invariant timescale hierarchy across the cortical somatosensory network.Proceedings of the National Academy of Sciences of the United States of America,118(3).
MLA	Rossi-Pool R.,et al."Invariant timescale hierarchy across the cortical somatosensory network".Proceedings of the National Academy of Sciences of the United States of America 118.3(2021).