气候变化领域集成服务门户(CCPortal): Area-specific thalamocortical synchronization underlies the transition from motor planning to execution

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DOI	10.1073/pnas.2012658118
	Area-specific thalamocortical synchronization underlies the transition from motor planning to execution
	Nashef A.; Mitelman R.; Harel R.; Joshua M.; Prut Y.
发表日期	2021
ISSN	00278424
卷号	118 期号:6
英文摘要	We studied correlated firing between motor thalamic and cortical cells in monkeys performing a delayed-response reaching task. Simultaneous recording of thalamocortical activity revealed that around movement onset, thalamic cells were positively correlated with cell activity in the primary motor cortex but negatively correlated with the activity of the premotor cortex. The differences in the correlation contrasted with the average neural responses, which were similar in all three areas. Neuronal correlations reveal functional cooperation and opposition between the motor thalamus and distinct motor cortical areas with specific roles in planning vs. performing movements. Thus, by enhancing and suppressing motor and premotor firing, the motor thalamus can facilitate the transition from a motor plan to execution. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Cerebellum; Motor cortex; Motor thalamus; Movement initiation; Nonhuman primates
语种	英语
scopus关键词	animal experiment; article; cell activity; cerebellum; Haplorhini; nerve potential; nonhuman; premotor cortex; primary motor cortex; thalamus
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180764
作者单位	Department of Medical Neurobiology, Hadassah Medical School, The Hebrew University, Jerusalem, 9112102, Israel; Institute of Medical Research Israel-Canada, Hadassah Medical School, The Hebrew University, Jerusalem, 9112102, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem, 9190401, Israel; Department of Neurosurgery, Sheba Medical Center, Tel Aviv, 5262000, Israel
推荐引用方式 GB/T 7714	Nashef A.,Mitelman R.,Harel R.,et al. Area-specific thalamocortical synchronization underlies the transition from motor planning to execution[J],2021,118(6).
APA	Nashef A.,Mitelman R.,Harel R.,Joshua M.,&Prut Y..(2021).Area-specific thalamocortical synchronization underlies the transition from motor planning to execution.Proceedings of the National Academy of Sciences of the United States of America,118(6).
MLA	Nashef A.,et al."Area-specific thalamocortical synchronization underlies the transition from motor planning to execution".Proceedings of the National Academy of Sciences of the United States of America 118.6(2021).