气候变化领域集成服务门户(CCPortal): Pattern formation and polarity sorting of driven actin filaments on lipid membranes

CCPortal

DOI	10.1073/pnas.2017047118
	Pattern formation and polarity sorting of driven actin filaments on lipid membranes
	Sciortino A.; Bausch A.R.
发表日期	2021
ISSN	00278424
卷号	118 期号:6
英文摘要	Collective motion of active matter is ubiquitously observed, ranging from propelled colloids to flocks of bird, and often features the formation of complex structures composed of agents moving coherently. However, it remains extremely challenging to predict emergent patterns from the binary interaction between agents, especially as only a limited number of interaction regimes have been experimentally observed so far. Here, we introduce an actin gliding assay coupled to a supported lipid bilayer, whose fluidity forces the interaction between self-propelled filaments to be dominated by steric repulsion. This results in filaments stopping upon binary collisions and eventually aligning nematically. Such a binary interaction rule results at high densities in the emergence of dynamic collectively moving structures including clusters, vortices, and streams of filaments. Despite the microscopic interaction having a nematic symmetry, the emergent structures are found to be polar, with filaments collectively moving in the same direction. This is due to polar biases introduced by the stopping upon collision, both on the individual filaments scale as well as on the scale of collective structures. In this context, positive half-charged topological defects turn out to be a most efficient trapping and polarity sorting conformation. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Actin motility assay; Active matter; High-density gliding assay; Ordering phenomena; Self-propelled rods
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180712
作者单位	Lehrstuhl für Biophysik (E27), Technische Universität München, Garching, D-85748, Germany; Center for Protein Assemblies, Garching, 85747, Germany
推荐引用方式 GB/T 7714	Sciortino A.,Bausch A.R.. Pattern formation and polarity sorting of driven actin filaments on lipid membranes[J],2021,118(6).
APA	Sciortino A.,&Bausch A.R..(2021).Pattern formation and polarity sorting of driven actin filaments on lipid membranes.Proceedings of the National Academy of Sciences of the United States of America,118(6).
MLA	Sciortino A.,et al."Pattern formation and polarity sorting of driven actin filaments on lipid membranes".Proceedings of the National Academy of Sciences of the United States of America 118.6(2021).