气候变化领域集成服务门户(CCPortal): Multisensory interactions regulate feeding behavior in Drosophila

CCPortal

DOI	10.1073/pnas.2004523118
	Multisensory interactions regulate feeding behavior in Drosophila
	Oh S.M.; Jeong K.; Seo J.T.; Moon S.J.
发表日期	2021
ISSN	00278424
卷号	118 期号:7
英文摘要	The integration of two or more distinct sensory cues can help animals make more informed decisions about potential food sources, but little is known about how feeding-related multimodal sensory integration happens at the cellular and molecular levels. Here, we show that multimodal sensory integration contributes to a stereotyped feeding behavior in the model organism Drosophila melanogaster. Simultaneous olfactory and mechanosensory inputs significantly influence a taste-evoked feeding behavior called the proboscis extension reflex (PER). Olfactory and mechanical information are mediated by antennal Or35a neurons and leg hair plate mechanosensory neurons, respectively. We show that the controlled delivery of three different sensory cues can produce a supra-additive PER via the concurrent stimulation of olfactory, taste, and mechanosensory inputs. We suggest that the fruit fly is a versatile model system to study multisensory integration related to feeding, which also likely exists in vertebrates. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Drosophila; Mechanosensation; Multisensory integration; Olfaction; Taste
语种	英语
scopus关键词	article; Drosophila melanogaster; feeding behavior; leg; nerve cell; nonhuman; reflex; vertebrate
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180652
作者单位	Department of Oral Biology, BK21 FOUR Project, Yonsei University College of Dentistry, Seodaemun-gu, Seoul, 03722, South Korea
推荐引用方式 GB/T 7714	Oh S.M.,Jeong K.,Seo J.T.,et al. Multisensory interactions regulate feeding behavior in Drosophila[J],2021,118(7).
APA	Oh S.M.,Jeong K.,Seo J.T.,&Moon S.J..(2021).Multisensory interactions regulate feeding behavior in Drosophila.Proceedings of the National Academy of Sciences of the United States of America,118(7).
MLA	Oh S.M.,et al."Multisensory interactions regulate feeding behavior in Drosophila".Proceedings of the National Academy of Sciences of the United States of America 118.7(2021).