气候变化领域集成服务门户(CCPortal): A switch to feeding on cycads generates parallel accelerated evolution of toxin tolerance in two clades of Eumaeus caterpillars (Lepidoptera: Lycaenidae)

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DOI	10.1073/pnas.2018965118
	A switch to feeding on cycads generates parallel accelerated evolution of toxin tolerance in two clades of Eumaeus caterpillars (Lepidoptera: Lycaenidae)
	Robbins R.K.; Cong Q.; Zhang J.; Shen J.; Riera J.Q.; Murray D.; Busby R.C.; Faynel C.; Hallwachs W.; Janzen D.H.; Grishin N.V.
发表日期	2021
ISSN	00278424
卷号	118 期号:7
英文摘要	We assembled a complete reference genome of Eumaeus atala, an aposematic cycad-eating hairstreak butterfly that suffered near extinction in the United States in the last century. Based on an analysis of genomic sequences of Eumaeus and 19 representative genera, the closest relatives of Eumaeus are Theorema and Mithras. We report natural history information for Eumaeus, Theorema, and Mithras. Using genomic sequences for each species of Eumaeus, Theorema, and Mithras (and three outgroups), we trace the evolution of cycad feeding, coloration, gregarious behavior, and other traits. The switch to feeding on cycads and to conspicuous coloration was accompanied by little genomic change. Soon after its origin, Eumaeus split into two fast evolving lineages, instead of forming a clump of close relatives in the phylogenetic tree. Significant overlap of the fast evolving proteins in both clades indicates parallel evolution. The functions of the fast evolving proteins suggest that the caterpillars developed tolerance to cycad toxins with a range of mechanisms including autophagy of damaged cells, removal of cell debris by macrophages, and more active cell proliferation. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Biodiversity; Butterflies; Genomics; Parallel evolution; Toxins
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180639
作者单位	Department of Entomology, National Museum of Natural History, Smithsonian Institution, Washington, DC 20013-7012, United States; McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390-8816, United States; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390-8816, United States; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390-8816, United States; Biology Department, Duke University, 130 Science Drive, Box 90338, Durham, NC 27708, United States; Estero, FL 34135, United States; Montaud, F-34160, France; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, United States; HHMI, University of Texas Southwestern Medical Center, Dallas, TX 75390-9050, United States
推荐引用方式 GB/T 7714	Robbins R.K.,Cong Q.,Zhang J.,et al. A switch to feeding on cycads generates parallel accelerated evolution of toxin tolerance in two clades of Eumaeus caterpillars (Lepidoptera: Lycaenidae)[J],2021,118(7).
APA	Robbins R.K..,Cong Q..,Zhang J..,Shen J..,Riera J.Q..,...&Grishin N.V..(2021).A switch to feeding on cycads generates parallel accelerated evolution of toxin tolerance in two clades of Eumaeus caterpillars (Lepidoptera: Lycaenidae).Proceedings of the National Academy of Sciences of the United States of America,118(7).
MLA	Robbins R.K.,et al."A switch to feeding on cycads generates parallel accelerated evolution of toxin tolerance in two clades of Eumaeus caterpillars (Lepidoptera: Lycaenidae)".Proceedings of the National Academy of Sciences of the United States of America 118.7(2021).