气候变化领域集成服务门户(CCPortal): Intracellular pathways for lignin catabolism in white-rot fungi

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DOI	10.1073/pnas.2017381118
	Intracellular pathways for lignin catabolism in white-rot fungi
	del Cerro C.; Erickson E.; Dong T.; Wong A.R.; Eder E.K.; Purvine S.O.; Mitchell H.D.; Weitz K.K.; Markillie L.M.; Burnet M.C.; Hoyt D.W.; Chu R.K.; Cheng J.-F.; Ramirez K.J.; Katahira R.; Xiong W.; Himmel M.E.; Subramanian V.; Linger J.G.; Salvachúa D.
发表日期	2021
ISSN	00278424
卷号	118 期号:9
英文摘要	Lignin is a biopolymer found in plant cell walls that accounts for 30% of the organic carbon in the biosphere. White-rot fungi (WRF) are considered the most efficient organisms at degrading lignin in nature. While lignin depolymerization by WRF has been extensively studied, the possibility that WRF are able to utilize lignin as a carbon source is still a matter of controversy. Here, we employ 13C-isotope labeling, systems biology approaches, and in vitro enzyme assays to demonstrate that two WRF, Trametes versicolor and Gelatoporia subvermispora, funnel carbon from lignin-derived aromatic compounds into central carbon metabolism via intracellular catabolic pathways. These results provide insights into global carbon cycling in soil ecosystems and furthermore establish a foundation for employing WRF in simultaneous lignin depolymerization and bioconversion to bioproducts-a key step toward enabling a sustainable bioeconomy. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Aromatic compounds; Carbon cycling; Gelatoporia subvermispora; Metabolism; Trametes versicolor
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180444
作者单位	Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, United States; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99354, United States; Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States; Biosciences Center, National Renewable Energy Laboratory, Golden, CO 80401, United States
推荐引用方式 GB/T 7714	del Cerro C.,Erickson E.,Dong T.,et al. Intracellular pathways for lignin catabolism in white-rot fungi[J],2021,118(9).
APA	del Cerro C..,Erickson E..,Dong T..,Wong A.R..,Eder E.K..,...&Salvachúa D..(2021).Intracellular pathways for lignin catabolism in white-rot fungi.Proceedings of the National Academy of Sciences of the United States of America,118(9).
MLA	del Cerro C.,et al."Intracellular pathways for lignin catabolism in white-rot fungi".Proceedings of the National Academy of Sciences of the United States of America 118.9(2021).