气候变化领域集成服务门户(CCPortal): Cingulo-opercular control network and disused motor circuits joined in standby mode

CCPortal

DOI	10.1073/pnas.2019128118
	Cingulo-opercular control network and disused motor circuits joined in standby mode
	Newbold D.J.; Gordon E.M.; Laumann T.O.; Seider N.A.; Montez D.F.; Gross S.J.; Zheng A.; Nielsen A.N.; Hoyt C.R.; Hampton J.M.; Ortega M.; Adeyemo B.; Miller D.B.; Van A.N.; Marek S.; Schlaggar B.L.; Carter A.R.; Kay B.P.; Greene D.J.; Raichle M.E.; Petersen S.E.; Snyder A.Z.; Dosenbach N.U.F.
发表日期	2021
ISSN	00278424
卷号	118 期号:13
英文摘要	Whole-brain resting-state functional MRI (rs-fMRI) during 2 wk of upper-limb casting revealed that disused motor regions became more strongly connected to the cingulo-opercular network (CON), an executive control network that includes regions of the dorsal anterior cingulate cortex (dACC) and insula. Disuse-driven increases in functional connectivity (FC) were specific to the CON and somatomotor networks and did not involve any other networks, such as the salience, frontoparietal, or default mode networks. Censoring and modeling analyses showed that FC increases during casting were mediated by large, spontaneous activity pulses that appeared in the disused motor regions and CON control regions. During limb constraint, disused motor circuits appear to enter a standby mode characterized by spontaneous activity pulses and strengthened connectivity to CON executive control regions. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Disuse; FMRI; Network neuroscience; Plasticity; Spontaneous activity
语种	英语
scopus关键词	article; cingulo opercular network; controlled study; default mode network; dorsal anterior cingulate cortex; executive network; functional connectivity; functional magnetic resonance imaging; insula; neuroscience; somatomotor network; upper limb; functional magnetic resonance imaging
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180087
作者单位	Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States; Institute for Innovations in Developmental Sciences, Northwestern University, Chicago, IL 60611, United States; Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63110, United States; Kennedy Krieger Institute, Baltimore, MD 21205, United States; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, ...
推荐引用方式 GB/T 7714	Newbold D.J.,Gordon E.M.,Laumann T.O.,et al. Cingulo-opercular control network and disused motor circuits joined in standby mode[J],2021,118(13).
APA	Newbold D.J..,Gordon E.M..,Laumann T.O..,Seider N.A..,Montez D.F..,...&Dosenbach N.U.F..(2021).Cingulo-opercular control network and disused motor circuits joined in standby mode.Proceedings of the National Academy of Sciences of the United States of America,118(13).
MLA	Newbold D.J.,et al."Cingulo-opercular control network and disused motor circuits joined in standby mode".Proceedings of the National Academy of Sciences of the United States of America 118.13(2021).