气候变化领域集成服务门户(CCPortal): Topological defects produce kinks in biopolymer filament bundles

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DOI	10.1073/pnas.2024362118
	Topological defects produce kinks in biopolymer filament bundles
	Slepukhin V.M.; Grill M.J.; Hu Q.; Botvinick E.L.; Wall W.A.; Levine A.J.
发表日期	2021
ISSN	00278424
卷号	118 期号:15
英文摘要	Bundles of stiff filaments are ubiquitous in the living world, found both in the cytoskeleton and in the extracellular medium. These bundles are typically held together by smaller cross-linking molecules. We demonstrate, analytically, numerically, and experimentally, that such bundles can be kinked, that is, have localized regions of high curvature that are long-lived metastable states. We propose three possible mechanisms of kink stabilization: a difference in trapped length of the filament segments between two cross-links, a dislocation where the endpoint of a filament occurs within the bundle, and the braiding of the filaments in the bundle. At a high concentration of cross-links, the last two effects lead to the topologically protected kinked states. Finally, we explore, numerically and analytically, the transition of the metastable kinked state to the stable straight bundle. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Bundles; Elasticity; Semiflexible filaments; Topological defects
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/179880
作者单位	Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1596, United States; Institute for Computational Mechanics, Technical University of Munich, Munich, 80333, Germany; Department of Biomedical Engineering, University of California, Irvine, CA 92697-2730, United States; Center for Complex Biological Systems, University of California, Irvine, CA 92697-2280, United States; Beckman Laser Institute, University of California, Irvine, CA 92697-2730, United States; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1596, United States; Department of Biomathematics, University of California, Los Angeles, CA 90095-1596, United States
推荐引用方式 GB/T 7714	Slepukhin V.M.,Grill M.J.,Hu Q.,et al. Topological defects produce kinks in biopolymer filament bundles[J],2021,118(15).
APA	Slepukhin V.M.,Grill M.J.,Hu Q.,Botvinick E.L.,Wall W.A.,&Levine A.J..(2021).Topological defects produce kinks in biopolymer filament bundles.Proceedings of the National Academy of Sciences of the United States of America,118(15).
MLA	Slepukhin V.M.,et al."Topological defects produce kinks in biopolymer filament bundles".Proceedings of the National Academy of Sciences of the United States of America 118.15(2021).