气候变化领域集成服务门户(CCPortal): Antagonistic activities of cotranscriptional regulators within an early developmental window set FLC expression level

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DOI	10.1073/pnas.2102753118
	Antagonistic activities of cotranscriptional regulators within an early developmental window set FLC expression level
	Schon M.; Baxter C.; Xu C.; Enugutti B.; Nodine M.D.; Dean C.
发表日期	2021
ISSN	00278424
卷号	118 期号:17
英文摘要	Quantitative variation in expression of the Arabidopsis floral repressor FLC influences whether plants overwinter before flowering, or have a rapid cycling habit enabling multiple generations a year. Genetic analysis has identified activators and repressors of FLC expression but how they interact to set expression level is poorly understood. Here, we show that antagonistic functions of the FLC activator FRIGIDA (FRI) and the repressor FCA, at a specific stage of embryo development, determine FLC expression and flowering. FRI antagonizes an FCA-induced proximal polyadenylation to increase FLC expression and delay flowering. Sector analysis shows that FRI activity during the early heart stage of embryo development maximally delays flowering. Opposing functions of cotranscriptional regulators during an early embryonic developmental window thus set FLC expression levels and determine flowering time. Results Regulation of FLC Polyadenylation Site Usage during Embryogenesis. © 2021 National Academy of Sciences. All rights reserved.
语种	英语
scopus关键词	antagonistic effect; article; embryo; embryo development; flower development; heart; polyadenylation; repressor gene
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/179755
作者单位	Gregor Mendel Institute, Vienna Biocenter, Vienna, 1030, Austria; Department of Cell & Developmental Biology, John Innes Centre, Norwich, NR4 7UH, United Kingdom; Laboratory of Molecular Biology, Wageningen University, Wageningen, 6708 PB, Netherlands
推荐引用方式 GB/T 7714	Schon M.,Baxter C.,Xu C.,et al. Antagonistic activities of cotranscriptional regulators within an early developmental window set FLC expression level[J],2021,118(17).
APA	Schon M.,Baxter C.,Xu C.,Enugutti B.,Nodine M.D.,&Dean C..(2021).Antagonistic activities of cotranscriptional regulators within an early developmental window set FLC expression level.Proceedings of the National Academy of Sciences of the United States of America,118(17).
MLA	Schon M.,et al."Antagonistic activities of cotranscriptional regulators within an early developmental window set FLC expression level".Proceedings of the National Academy of Sciences of the United States of America 118.17(2021).