气候变化领域集成服务门户(CCPortal): Chronic thromboembolic pulmonary hypertension: Evaluation of V/Q SPECT/CT and V/Q Quotient SPECT findings with postoperative results of pulmonary endarterectomy

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DOI	10.1097/MNM.0000000000001348
	Chronic thromboembolic pulmonary hypertension: Evaluation of V/Q SPECT/CT and V/Q Quotient SPECT findings with postoperative results of pulmonary endarterectomy
	Ozguven S.; Ones T.; Bozkurtlar E.; Yanartas M.; Tas S.; Inanir S.; Turoglu H.T.; Erdil T.Y.; Yildizeli B.
发表日期	2021
ISSN	1433636
起始页码	369
结束页码	377
英文摘要	Objectives We aimed to perform a comparison between V/Q single-photon emission computed tomography/computed tomography (SPECT/CT) and V/Q Quotient single-photon emission computerized tomography (SPECT) in the detection of chronic thromboembolic pulmonary hypertension (CTEPH) and in depicting the extent of the disease on per-segment basis in patients with CTEPH. Methods Between January 2015 and November 2019, a total of 412 patients with pulmonary hypertension secondary to CTEPH at the preoperative assessment underwent pulmonary endarterectomy (PEA), of whom 92 consecutive patients with their V/Q SPECT/CT scans have been performed in our institution prior to PEA were included in this study. Histopathological findings and post-PEA fully resected surgical specimens were used as the reference standard. Results On a per-patient basis analysis, V/Q SPECT/CT and V/Q Quotient SPECT both revealed CTEPH in the same 85 of the 92 patients (κ = 1) with a detection rate of 92.4%. In six of these patients, chronic thromboembolic disease could not be reported on both of these two methods due to extensive 'matched' V/Q defects. On a per-segment basis analysis, V/Q SPECT/CT and V/Q Quotient SPECT showed a sensitivity of 75.8 and 73.1%, respectively. Correlation analysis results showed a significant correlation (κ = 0.933) between these two methods on a per-segment basis analysis. Conclusion In the light of histopathological findings and post-PEA surgical specimen examinations, the results of the present study indicated that both V/Q SPECT/CT and V/Q Quotient SPECT showed relatively high efficacy for the detection of CTEPH on per-patient and per-segment bases with an excellent agreement. © 2021 Lippincott Williams and Wilkins. All rights reserved.
英文关键词	endarterectomy; hypertension; pulmonary; pulmonary embolism; single-photon emission computed tomography/computed tomography; Ventilation-perfusion scan
来源期刊	Nuclear Medicine Communications
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/177293
作者单位	Departments of A Nuclear Medicine; Pathology, Marmara University Pendik Training, Research Hospital; Department of Cardiovascular Surgery, Health Sciences University Kartal Koşuyolu Training, Research Hospital; Department of Thoracic Surgery, Marmara University Pendik Training, Research Hospital, Istanbul, Turkey
推荐引用方式 GB/T 7714	Ozguven S.,Ones T.,Bozkurtlar E.,et al. Chronic thromboembolic pulmonary hypertension: Evaluation of V/Q SPECT/CT and V/Q Quotient SPECT findings with postoperative results of pulmonary endarterectomy[J],2021.
APA	Ozguven S..,Ones T..,Bozkurtlar E..,Yanartas M..,Tas S..,...&Yildizeli B..(2021).Chronic thromboembolic pulmonary hypertension: Evaluation of V/Q SPECT/CT and V/Q Quotient SPECT findings with postoperative results of pulmonary endarterectomy.Nuclear Medicine Communications.
MLA	Ozguven S.,et al."Chronic thromboembolic pulmonary hypertension: Evaluation of V/Q SPECT/CT and V/Q Quotient SPECT findings with postoperative results of pulmonary endarterectomy".Nuclear Medicine Communications (2021).