气候变化领域集成服务门户(CCPortal): Epidemiological characteristics of tuberculosis and effects of meteorological factors and air pollutants on tuberculosis in Shijiazhuang; China: A distribution lag non-linear analysis

CCPortal

DOI	10.1016/j.envres.2020.110310
	Epidemiological characteristics of tuberculosis and effects of meteorological factors and air pollutants on tuberculosis in Shijiazhuang; China: A distribution lag non-linear analysis
	Wang W.; Guo W.; Cai J.; Guo W.; Liu R.; Liu X.; Ma N.; Zhang X.; Zhang S.
发表日期	2021
ISSN	139351
卷号	195
英文摘要	Background: Tuberculosis (TB) is a serious public health problem in China. There is evidence to prove that meteorological factors and exposure to air pollutants have a certain impact on TB. But the evidence of this relationship is insufficient, and the conclusions are inconsistent. Methods: Descriptive epidemiological methods were used to describe the distribution characteristics of TB in Shijiazhuang in the past five years. Through the generalized linear regression model (GLM) and the generalized additive model (GAM), the risk factors that affect the incidence of TB are screened. A combination of GLM and distribution lag nonlinear model (DLNM) was used to evaluate the lag effect of environmental factors on the TB. Results were tested for robustness by sensitivity analysis. Results: The incidence of TB in Shijiazhuang showed a downward trend year by year, with seasonality and periodicity. Every 10 μg/m3 of PM10 changes, the RR distribution is bimodal. The first peak of RR occurs on the second day of lag (RR = 1.00166, 95% CI: 1.00023, 1.00390); the second risk period starts from 13th day of lag and peaks on15th day (RR = 1.00209, 95% CI: 1.00076, 1.00341), both of which are statistically significant. The cumulative effect of increasing 10 μg/m3 showed a similar bimodal distribution. Time zones where the RR makes sense are days 4–6 and 13–20. RR peaked on the 18th day (RR = 1.02239, 95% CI: 1.00623, 1.03882). The RR has a linear relationship with the concentration. Under the same concentration, the RR peaks within 15–20 days. Conclusion: TB in Shijiazhuang City showed a downward trend year by year, with obvious seasonal fluctuations. The air pollutant PM10 increases the risk of TB. The development of TB has a short-term lag and cumulative lag effects. We should focus on protecting susceptible people from TB in spring and autumn, and strengthen the monitoring and emission management of PM10 in the atmosphere. © 2020 Elsevier Inc.
英文关键词	Air pollution; DLNM; Epidemic characteristics; GAM; GLM; Tuberculosis
scopus关键词	carbon monoxide; nitrogen dioxide; ozone; sulfur dioxide; atmospheric pollution; climate effect; detection method; disease incidence; environmental factor; epidemiology; nonlinearity; particulate matter; pollution effect; tuberculosis; adolescent; adult; age; aged; air pollutant; air pollution; autumn; child; China; concentration (parameter); controlled study; correlation coefficient; descriptive research; environmental factor; epidemic; female; human; linear regression analysis; lung tuberculosis; major clinical study; male; mathematical model; meteorological phenomena; middle aged; nonlinear system; occupation; particulate matter 10; periodicity; priority journal; seasonal variation; sensitivity analysis; spring; susceptible population; China
来源期刊	Environmental Research
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/177204
作者单位	Department of Epidemiology and Statistics, School of Public Health, Hebei Medical University, Hebei Province Key Laboratory of Environment and Human Health, Shijiazhuang, China; Department of Epidemic Control and Prevention, Center for Disease Prevention and Control of Shijiazhuang City, Shijiazhuang, China
推荐引用方式 GB/T 7714	Wang W.,Guo W.,Cai J.,et al. Epidemiological characteristics of tuberculosis and effects of meteorological factors and air pollutants on tuberculosis in Shijiazhuang; China: A distribution lag non-linear analysis[J],2021,195.
APA	Wang W..,Guo W..,Cai J..,Guo W..,Liu R..,...&Zhang S..(2021).Epidemiological characteristics of tuberculosis and effects of meteorological factors and air pollutants on tuberculosis in Shijiazhuang; China: A distribution lag non-linear analysis.Environmental Research,195.
MLA	Wang W.,et al."Epidemiological characteristics of tuberculosis and effects of meteorological factors and air pollutants on tuberculosis in Shijiazhuang; China: A distribution lag non-linear analysis".Environmental Research 195(2021).