气候变化领域集成服务门户(CCPortal): Ancient genomes from present-day France unveil 7;000 years of its demographic history

CCPortal

DOI	10.1073/pnas.1918034117
	Ancient genomes from present-day France unveil 7;000 years of its demographic history
	Brunel S.; Andrew Bennett E.; Cardin L.; Garraud D.; Emam H.B.; Beylier A.; Boulestin B.; Chenal F.; Ciesielski E.; Convertini F.; Dedet B.; Desbrosse-Degobertiere S.; Desenne S.; Dubouloz J.; Duday H.; Escalon G.; Fabre V.; Gailledrat E.; Gandelin M.; Gleize Y.; Goepfert S.; Guilaine J.; Hachem L.; Ilett M.; Lambach F.; Maziere F.; Perrin B.; Plouin S.; Pinard E.; Praud I.; Richard I.; Riquier V.; Roure R.; Sendra B.; Thevenet C.; Thiol S.; Vauquelin E.; Vergnaud L.; Grange T.; Geigl E.-M.; Pruvost M.
发表日期	2020
ISSN	0027-8424
起始页码	12791
结束页码	12798
卷号	117 期号:23
英文摘要	Genomic studies conducted on ancient individuals across Europe have revealed how migrations have contributed to its present genetic landscape, but the territory of present-day France has yet to be connected to the broader European picture. We generated a large dataset comprising the complete mitochondrial genomes, Y-chromosome markers, and genotypes of a number of nuclear loci of interest of 243 individuals sampled across present-day France over a period spanning 7,000 y, complemented with a partially overlapping dataset of 58 low-coverage genomes. This panel provides a high-resolution transect of the dynamics of maternal and paternal lineages in France as well as of autosomal genotypes. Parental lineages and genomic data both revealed demographic patterns in France for the Neolithic and Bronze Age transitions consistent with neighboring regions, first with a migration wave of Anatolian farmers followed by varying degrees of admixture with autochthonous hunter-gatherers, and then substantial gene flow from individuals deriving part of their ancestry from the Pontic steppe at the onset of the Bronze Age. Our data have also highlighted the persistence of Magdalenian-associated ancestry in hunter-gatherer populations outside of Spain and thus provide arguments for an expansion of these populations at the end of the Paleolithic Period more northerly than what has been described so far. Finally, no major demographic changes were detected during the transition between the Bronze and Iron Ages. © 2020 National Academy of Sciences. All rights reserved.
英文关键词	Migration; Neolithic; Paleogenomics; Population genomics; Protohistory
语种	英语
scopus关键词	adult; agricultural worker; Bronze Age; chromosome marker; controlled study; demography; female; France; gene flow; genomics; genotype; human; human experiment; human tissue; hunter-gatherer; Iron Age; major clinical study; male; mitochondrial genome; Neolithic; Paleolithic; review; Spain; steppe; Y chromosome; France; genetic polymorphism; genetics; human genome; migration; molecular evolution; population; ancient DNA; mitochondrial DNA; Chromosomes, Human, Y; DNA, Ancient; DNA, Mitochondrial; Evolution, Molecular; Female; France; Gene Flow; Genome, Human; Human Migration; Humans; Male; Polymorphism, Genetic; Population
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160934
作者单位	Brunel, S., Université de Paris, CNRS, Institut Jacques Monod, UMR 7592, Paris Cedex 13, 75205, France; Andrew Bennett, E., Université de Paris, CNRS, Institut Jacques Monod, UMR 7592, Paris Cedex 13, 75205, France; Cardin, L., Université de Paris, CNRS, Institut Jacques Monod, UMR 7592, Paris Cedex 13, 75205, France, Institut de Recherche Criminelle de la Gendarmerie Nationale, Pontoise, 95000, France; Garraud, D., Université de Paris, CNRS, Institut Jacques Monod, UMR 7592, Paris Cedex 13, 75205, France, Institut de Recherche Criminelle de la Gendarmerie Nationale, Pontoise, 95000, France; Emam, H.B., ANTEA-Archéologie, Habsheim, 68440, France, UMR 7044 Archéologie et Histoire ancienne: Méditerranée - Europe (ArcHiMèdE), CNRS, Université de Strasbourg, Strasbourg Cedex, 67083, France; Beylier, A., Service Archéologie Sète Agglopôle Mediterranée, Frontignan, 34110, France, UMR 5140 Archéologie des Sociétés Méditerranéennes (ASM), CNRS, Université Paul Valéry Montpellier 3, Montpellier, 34199, France; Bou...
推荐引用方式 GB/T 7714	Brunel S.,Andrew Bennett E.,Cardin L.,et al. Ancient genomes from present-day France unveil 7;000 years of its demographic history[J],2020,117(23).
APA	Brunel S..,Andrew Bennett E..,Cardin L..,Garraud D..,Emam H.B..,...&Pruvost M..(2020).Ancient genomes from present-day France unveil 7;000 years of its demographic history.Proceedings of the National Academy of Sciences of the United States of America,117(23).
MLA	Brunel S.,et al."Ancient genomes from present-day France unveil 7;000 years of its demographic history".Proceedings of the National Academy of Sciences of the United States of America 117.23(2020).