气候变化领域集成服务门户(CCPortal): Auxin methylation is required for differential growth in Arabidopsis

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DOI	10.1073/pnas.1806565115
	Auxin methylation is required for differential growth in Arabidopsis
	Abbas M.; Hernández-García J.; Pollmann S.; Samodelov S.L.; Kolb M.; Friml J.; Hammes U.Z.; Zurbriggen M.D.; Blázquez M.A.; Alabadí D.
发表日期	2018
ISSN	0027-8424
起始页码	6864
结束页码	6869
卷号	115 期号:26
英文摘要	Asymmetric auxin distribution is instrumental for the differential growth that causes organ bending on tropic stimuli and curvatures during plant development. Local differences in auxin concentrations are achieved mainly by polarized cellular distribution of PIN auxin transporters, but whether other mechanisms involving auxin homeostasis are also relevant for the formation of auxin gradients is not clear. Here we show that auxin methylation is required for asymmetric auxin distribution across the hypocotyl, particularly during its response to gravity. We found that loss-of-function mutants in Arabidopsis IAA CARBOXYL METHYLTRANSFERASE1 (IAMT1) prematurely unfold the apical hook, and that their hypocotyls are impaired in gravitropic reorientation. This defect is linked to an auxin-dependent increase in PIN gene expression, leading to an increased polar auxin transport and lack of asymmetric distribution of PIN3 in the iamt1 mutant. Gravitropic reorientation in the iamt1 mutant could be restored with either endodermis-specific expression of IAMT1 or partial inhibition of polar auxin transport, which also results in normal PIN gene expression levels. We propose that IAA methylation is necessary in gravity-sensing cells to restrict polar auxin transport within the range of auxin levels that allow for differential responses. © 2018 National Academy of Sciences. All Rights Reserved.
英文关键词	Auxin metabolism; Gravitropism; Homeostasis; Hormone regulation
语种	英语
scopus关键词	auxin; protein carboxyl methyltransferase; Arabidopsis protein; IAMT1 protein, Arabidopsis; indoleacetic acid derivative; methyltransferase; PIN3 protein, Arabidopsis; Arabidopsis; Article; controlled study; endodermis; gene expression; gene location; gravity; hypocotyl; IAMT1 gene; loss of function mutation; nonhuman; PIN gene; PIN3 gene; plant cell; plant gene; plant growth; priority journal; protein methylation; protein transport; Arabidopsis; biosynthesis; gene expression regulation; genetics; growth, development and aging; metabolism; methylation; mutation; physiology; Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Plant; Hypocotyl; Indoleacetic Acids; Methylation; Methyltransferases; Mutation
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160501
作者单位	Abbas, M., Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas–Universidad Politécnica de Valencia, Valencia, 46022, Spain, Institute of Science and Technology Austria, Klosterneuburg, 3400, Austria, Plant and Crop Science, University of Nottingham, Loughborough, LE12 5RD, United Kingdom; Hernández-García, J., Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas–Universidad Politécnica de Valencia, Valencia, 46022, Spain; Pollmann, S., Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid, Instituto Nacional de Investigación y Tecnología Agraria y Alimentación, Pozuelo de Alarcón, 28223, Spain; Samodelov, S.L., Institute of Synthetic Biology and Cluster of Excellence in Plant Sciences, University of Düsseldorf, Düsseldorf, 40225, Germany, Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, 79085, Germany, Department of Clinical Pharmacology and Toxico...
推荐引用方式 GB/T 7714	Abbas M.,Hernández-García J.,Pollmann S.,et al. Auxin methylation is required for differential growth in Arabidopsis[J],2018,115(26).
APA	Abbas M..,Hernández-García J..,Pollmann S..,Samodelov S.L..,Kolb M..,...&Alabadí D..(2018).Auxin methylation is required for differential growth in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America,115(26).
MLA	Abbas M.,et al."Auxin methylation is required for differential growth in Arabidopsis".Proceedings of the National Academy of Sciences of the United States of America 115.26(2018).