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DOI	10.1073/pnas.1810394116
	Form and function of F-actin during biomineralization revealed from live experiments on foraminifera
	Tyszka J.; Bickmeyer U.; Raitzsch M.; Bijma J.; Kaczmarek K.; Mewes A.; Topa P.; Janse M.
发表日期	2019
ISSN	0027-8424
起始页码	4111
结束页码	4116
卷号	116 期号:10
英文摘要	Although the emergence of complex biomineralized forms has been investigated for over a century, still little is known on how single cells control morphology of skeletal structures, such as frustules, shells, spicules, or scales. We have run experiments on the shell formation in foraminifera, unicellular, mainly marine organisms that can build shells by successive additions of chambers. We used live imaging to discover that all stages of chamber/shell formation are controlled by dedicated actin-driven pseudopodial structures. Successive reorganization of an F-actin meshwork, associated with microtubular structures, is actively involved in formation of protective envelope, followed by dynamic scaffolding of chamber morphology. Then lamellar dynamic templates create a confined space and control mineralization separated from seawater. These observations exclude extracellular calcification assumed in selected foraminiferal clades, and instead suggest a semiintracellular biomineralization pattern known from other unicellular calcifying and silicifying organisms. These results give a challenging prospect to decipher the vital effect on geochemical proxies applied to paleoceanographic reconstructions. They have further implications for understanding multiscale complexity of biomineralization and show a prospect for material science applications. © 2019 National Academy of Sciences. All Rights Reserved.
英文关键词	Biomineralization; Cytoskeleton; Foraminifera; Morphogenesis; Shells
语种	英语
scopus关键词	F actin; sea water; actin; protozoal protein; animal shell; Article; biomineralization; calcification; foraminifer; geochemistry; microtubule; morphogenesis; priority journal; protein function; protein structure; pseudopodium; actin filament; biomineralization; foraminifer; metabolism; physiology; Actin Cytoskeleton; Actins; Biomineralization; Foraminifera; Protozoan Proteins
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160399
作者单位	Tyszka, J., Research Centre in Kraków, Institute of Geological Sciences, Polish Academy of Sciences, Kraków, 31-002, Poland; Bickmeyer, U., Ecological Chemistry, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Bremerhaven, D-27570, Germany; Raitzsch, M., Marine Biogeosciences, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Bremerhaven, D-27570, Germany, Institut für Mineralogie, Leibniz Universität Hannover, Hannover, 30167, Germany; Bijma, J., Marine Biogeosciences, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Bremerhaven, D-27570, Germany; Kaczmarek, K., Marine Biogeosciences, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Bremerhaven, D-27570, Germany; Mewes, A., Marine Biogeosciences, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Bremerhaven, D-27570, Germany; Topa, P., Department of Computer Science, AGH University of Science and Technology, Kraków, 30-052, Poland; ...
推荐引用方式 GB/T 7714	Tyszka J.,Bickmeyer U.,Raitzsch M.,et al. Form and function of F-actin during biomineralization revealed from live experiments on foraminifera[J],2019,116(10).
APA	Tyszka J..,Bickmeyer U..,Raitzsch M..,Bijma J..,Kaczmarek K..,...&Janse M..(2019).Form and function of F-actin during biomineralization revealed from live experiments on foraminifera.Proceedings of the National Academy of Sciences of the United States of America,116(10).
MLA	Tyszka J.,et al."Form and function of F-actin during biomineralization revealed from live experiments on foraminifera".Proceedings of the National Academy of Sciences of the United States of America 116.10(2019).