气候变化领域集成服务门户(CCPortal): Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient

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DOI	10.1073/pnas.1916935117
	Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient
	Kaplan M.; Sweredoski M.J.; Rodrigues J.P.G.L.M.; Tocheva E.I.; Chang Y.-W.; Ortega D.R.; Beeby M.; Jensen G.J.
发表日期	2020
ISSN	0027-8424
起始页码	8941
结束页码	8947
卷号	117 期号:16
英文摘要	The bacterial flagellum is an amazing nanomachine. Understanding how such complex structures arose is crucial to our understanding of cellular evolution. We and others recently reported that in several Gammaproteobacterial species, a relic subcomplex comprising the decorated P and L rings persists in the outer membrane after flagellum disassembly. Imaging nine additional species with cryoelectron tomography, here, we show that this subcomplex persists after flagellum disassembly in other phyla as well. Bioinformatic analyses fail to show evidence of any recent horizontal transfers of the P- and L-ring genes, suggesting that this subcomplex and its persistence is an ancient and conserved feature of the flagellar motor. We hypothesize that one function of the P and L rings is to seal the outer membrane after motor disassembly. © 2020 National Academy of Sciences. All rights reserved.
英文关键词	Cryo-electron tomography; Evolution; Flagellar motor
语种	英语
scopus关键词	article; electron tomography; flagellum; outer membrane; bacterial gene; bacterial outer membrane; bacterium; biology; cryoelectron microscopy; cytology; electron tomography; genetics; metabolism; phylogeny; species differentiation; ultrastructure; bacterial protein; flgI protein, Bacteria; outer membrane protein; Bacteria; Bacterial Outer Membrane; Bacterial Outer Membrane Proteins; Bacterial Proteins; Computational Biology; Cryoelectron Microscopy; Electron Microscope Tomography; Flagella; Genes, Bacterial; Genetic Speciation; Phylogeny
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160299
作者单位	Kaplan, M., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States; Sweredoski, M.J., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States; Rodrigues, J.P.G.L.M., Department of Structural Biology, Stanford University, Stanford, CA 94305, United States; Tocheva, E.I., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States, Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Chang, Y.-W., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Ortega, D.R., Division of Biology and Biological Engineering, California Institute of Technolog...
推荐引用方式 GB/T 7714	Kaplan M.,Sweredoski M.J.,Rodrigues J.P.G.L.M.,et al. Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient[J],2020,117(16).
APA	Kaplan M..,Sweredoski M.J..,Rodrigues J.P.G.L.M..,Tocheva E.I..,Chang Y.-W..,...&Jensen G.J..(2020).Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient.Proceedings of the National Academy of Sciences of the United States of America,117(16).
MLA	Kaplan M.,et al."Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient".Proceedings of the National Academy of Sciences of the United States of America 117.16(2020).