气候变化领域集成服务门户(CCPortal): Formation of nucleobases in a Miller-Urey reducing atmosphere

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DOI	10.1073/pnas.1700010114
	Formation of nucleobases in a Miller-Urey reducing atmosphere
	Ferus M.; Pietrucci F.; Saitta A.M.; Knížek A.; Kubelík P.; Ivanek O.; Shestivska V.; Civiš S.
发表日期	2017
ISSN	0027-8424
起始页码	4306
结束页码	4311
卷号	114 期号:17
英文摘要	The Miller-Urey experiments pioneered modern research on the molecular origins of life, but their actual relevance in this field was later questioned because the gas mixture used in their research is considered too reducing with respect to the most accepted hypotheses for the conditions on primordial Earth. In particular, the production of only amino acids has been taken as evidence of the limited relevance of the results. Here, we report an experimental work, combined with state-of-the-art computational methods, in which both electric discharge and laser-driven plasma impact simulations were carried out in a reducing atmosphere containing NH3 + CO. We show that RNA nucleobases are synthesized in these experiments, strongly supporting the possibility of the emergence of biologically relevant molecules in a reducing atmosphere. The reconstructed synthetic pathways indicate that small radicals and formamide play a crucial role, in agreement with a number of recent experimental and theoretical results.
英文关键词	Asteroid impact; Life origins; Reducing atmosphere
语种	英语
scopus关键词	ammonia; carbon monoxide; formamide; nucleic acid base; RNA; formamide derivative; Article; atmosphere; plasma gas; priority journal; RNA synthesis; shock wave; simulation; astronomy; atmosphere; biogenesis; chemical model; chemistry; oxidation reduction reaction; Ammonia; Atmosphere; Carbon Monoxide; Evolution, Chemical; Formamides; Models, Chemical; Origin of Life; Oxidation-Reduction; RNA
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/158970
作者单位	Ferus, M., J. Heyrovský Institute of Physical Chemistry, Czech Academy of Sciences, Prague 8, CZ18223, Czech Republic; Pietrucci, F., Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie, Université Pierre et Marie Curie, Sorbonne Universités, CNRS, Muséum National d'Histoire Naturelle, Institut de Recherche pour le Développement, UMR 7590, Paris, F-75005, France; Saitta, A.M., Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie, Université Pierre et Marie Curie, Sorbonne Universités, CNRS, Muséum National d'Histoire Naturelle, Institut de Recherche pour le Développement, UMR 7590, Paris, F-75005, France; Knížek, A., J. Heyrovský Institute of Physical Chemistry, Czech Academy of Sciences, Prague 8, CZ18223, Czech Republic, Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University in Prague, Prague 2, CZ12840, Czech Republic; Kubelík, P., J. Heyrovský Institute of Physical Chemistry, Czech Academy of Sciences, Prague 8, CZ18223, Czech Repub...
推荐引用方式 GB/T 7714	Ferus M.,Pietrucci F.,Saitta A.M.,et al. Formation of nucleobases in a Miller-Urey reducing atmosphere[J],2017,114(17).
APA	Ferus M..,Pietrucci F..,Saitta A.M..,Knížek A..,Kubelík P..,...&Civiš S..(2017).Formation of nucleobases in a Miller-Urey reducing atmosphere.Proceedings of the National Academy of Sciences of the United States of America,114(17).
MLA	Ferus M.,et al."Formation of nucleobases in a Miller-Urey reducing atmosphere".Proceedings of the National Academy of Sciences of the United States of America 114.17(2017).