气候变化领域集成服务门户(CCPortal): Psychoactive substances in mussels: Analysis and occurrence assessment

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DOI	10.1016/j.marpolbul.2019.07.042
	Psychoactive substances in mussels: Analysis and occurrence assessment
	López-García E.; Postigo C.; López de Alda M.
发表日期	2019
ISSN	0025326X
起始页码	985
结束页码	992
卷号	146
英文摘要	This work presents an analytical methodology based on a “Quick, easy, cheap, effective, rugged, and safe” (QuEChERS) extraction and liquid chromatography-tandem mass spectrometry detection (LC-MS/MS) for the simultaneous determination of 35 psychoactive substances in fresh mussel samples. The compounds investigated include illicit drugs, new psychoactive substances, commonly prescribed psychiatric pharmaceuticals, and caffeine. The methodology was validated in terms of recovery (relative recoveries 77–118%), repeatability (relative standard deviation values <20%), and sensitivity (limits of detection and quantification <2 ng/g fresh weight (f.w.) and <6.7 ng/g f.w., respectively, for most compounds). The method was applied to the analysis of 15 samples, covering both commercially available mussels purchased from local food markets and wild fresh mussels collected in the Northeast coast of Spain in the Mediterranean Sea. Only one sample corresponding to wild mussels was found to contain 2 of the target analytes, namely, sertraline (1.5 ng/g f.w.) and caffeine, (12.8 ng/g f.w.). © 2019 Elsevier Ltd
英文关键词	Antidepressants; Benzodiazepines; Biota; Drugs of abuse; Liquid chromatography-tandem mass spectrometry; QuEChERS
语种	英语
scopus关键词	Caffeine; Drug products; Mass spectrometry; Molluscs; Antidepressants; Benzodiazepines; Biota; Drugs of abuse; Liquid chromatography-tandem mass spectrometry; Quechers; Liquid chromatography; amphetamine; antidepressant agent; benzodiazepine; caffeine; cannabinoid; central stimulant agent; cocaine; hypnotic agent; illicit drug; neuroleptic agent; opiate; psychedelic agent; psychotropic agent; sedative agent; sertraline; psychotropic agent; bioaccumulation; biota; bivalve; drug; extraction method; liquid chromatography; mass spectrometry; Article; controlled study; fresh weight; limit of detection; limit of quantitation; liquid chromatography-mass spectrometry; measurement repeatability; Mediterranean Sea; mussel; nonhuman; sampling; Spain; animal; bivalve; chemistry; liquid chromatography; sea food; solid phase extraction; tandem mass spectrometry; water pollutant; Mediterranean Coast [Spain]; Spain; Animals; Bivalvia; Chromatography, Liquid; Mediterranean Sea; Psychotropic Drugs; Seafood; Solid Phase Extraction; Spain; Tandem Mass Spectrometry; Water Pollutants, Chemical
来源期刊	Marine Pollution Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/149650
作者单位	Water, Environmental and Food Chemistry (ENFOCHEM) Research Group, Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona 18-26, Barcelona, 08034, Spain
推荐引用方式 GB/T 7714	López-García E.,Postigo C.,López de Alda M.. Psychoactive substances in mussels: Analysis and occurrence assessment[J],2019,146.
APA	López-García E.,Postigo C.,&López de Alda M..(2019).Psychoactive substances in mussels: Analysis and occurrence assessment.Marine Pollution Bulletin,146.
MLA	López-García E.,et al."Psychoactive substances in mussels: Analysis and occurrence assessment".Marine Pollution Bulletin 146(2019).