气候变化领域集成服务门户(CCPortal): Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil

CCPortal

DOI	10.1016/j.marpolbul.2020.110975
	Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil
	Monteiro F.; Lemos L.S.; de Moura J.F.; Rocha R.C.C.; Moreira I.; Di Beneditto A.P.M.; Kehrig H.A.; Bordon I.C.; Siciliano S.; Saint'Pierre T.D.; Hauser-Davis R.A.
发表日期	2020
ISSN	0025326X
卷号	153
英文摘要	Titanium (Ti), used in many dailyuse products, such as shampoos and sunscreen filters, in the form of TiO2 nanoparticles (NPs), may elicit adverse marine biota effects. Marine mammal Ti data is scarce, and subcellular distribution and detoxification information is non-existent. Ti concentrations and metalloprotein detoxification in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil were assessed. Metallothionein (MT) concentrations were determined spectrophotometrically, total and subcellular Ti, by ICP-MS and detoxification, by HPLC-ICP-MS. Ti detoxification occurred through MT complexation. Statistical Ti-MT associations were observed in S. bredanensis liver, indicating TiO2 NPs contamination, as Ti binds to MT only as NPs. MT-Ti correlations were observed for both the coastal (P. blainvillei) and offshore (S. bredanensis) dolphins, evidencing oceanic TiO2 diffusion. Ti detoxification through binding to reduced glutathione occurred in both species. Thermostable subcellular fractions are a valuable tool for cetacean Ti detoxification assessments and should be applied to conservation efforts. © 2020 Elsevier Ltd
英文关键词	Bioavailability; Delphinids; Detoxification; Metalloproteins; TiO2 nanoparticles; Titanium
语种	英语
scopus关键词	Biochemistry; Dolphins (structures); Inductively coupled plasma mass spectrometry; Mammals; Mass spectrometers; Nanoparticles; Offshore oil well production; Oxide minerals; Proteins; TiO2 nanoparticles; Titanium; Titanium dioxide; Bioavailability; Delphinids; Detoxification process; Metallo-proteins; Reduced glutathione; Southeastern Brazil; Subcellular distribution; Subcellular fractions; Detoxification; glutathione; metallothionein; titanium; titanium; bioavailability; concentration (composition); detoxification; dolphin; metallothionein; nanoparticle; spatial distribution; titanium; animal tissue; Article; bioaccumulation; Brazil; cellular distribution; complex formation; Delphinidae; detoxification; female; inductively coupled plasma mass spectrometry; liquid chromatography-mass spectrometry; liver; male; nonhuman; Pontoporia blainvillei; spectrophotometry; Steno bredanensis; animal; drug inactivation; metabolism; toothed whale; water pollutant; Brazil; Cetacea; Delphinidae; Mammalia; Pontoporia blainvillei; Steno bredanensis; Animals; Brazil; Dolphins; Inactivation, Metabolic; Titanium; Water Pollutants, Chemical
来源期刊	Marine Pollution Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/149124
作者单位	Departamento de Química, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rua Marquês de São Vicente, 225, Gávea, Rio de Janeiro, RJ 22453-900, Brazil; Grupo de Estudos de Mamíferos Marinhos da Região dos Lagos (GEMM-Lagos), Rua São José 1.260, Praia Seca, Araruama, RJ 28970-000, Brazil; Marine Mammal Institute, Hatfield Marine Science Center, Oregon State University, 2030 SE Marine Science Dr, Newport, OR 97365, United States; Leibniz Center for Tropical Marine Ecology – ZMT, Systems Ecology Group, Fahrenheitstraße 6, Bremen, 28359, Germany; Universidade Estadual do Norte Fluminense, Laboratório de Ciências Ambientais, Campos dos Goytacazes, RJ 28013-602, Brazil; UNESP - Universidade Estadual Paulista, Campus do Litoral Paulista, Núcleo de Estudos em Poluição e Ecotoxicologia Aquática (NEPEA), Praça Infante Dom Henrique s/n°, Parque Bitaru, São Vicente, SP 11330-900, Brazil; Laboratório de Biodiversidade, Instituto Oswaldo Cruz, Fiocruz, Pavilhão Mourisco sala 217, Av. Brasil, 4.365, Ma...
推荐引用方式 GB/T 7714	Monteiro F.,Lemos L.S.,de Moura J.F.,et al. Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil[J],2020,153.
APA	Monteiro F..,Lemos L.S..,de Moura J.F..,Rocha R.C.C..,Moreira I..,...&Hauser-Davis R.A..(2020).Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil.Marine Pollution Bulletin,153.
MLA	Monteiro F.,et al."Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil".Marine Pollution Bulletin 153(2020).