气候变化领域集成服务门户(CCPortal): Shewanella algae and Vibrio spp. strains isolated in Italian aquaculture farms are reservoirs of antibiotic resistant genes that might constitute a risk for human health

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DOI	10.1016/j.marpolbul.2020.111057
	Shewanella algae and Vibrio spp. strains isolated in Italian aquaculture farms are reservoirs of antibiotic resistant genes that might constitute a risk for human health
	Zago V.; Veschetti L.; Patuzzo C.; Malerba G.; Lleo M.M.
发表日期	2020
ISSN	0025326X
卷号	154
英文摘要	The aquatic environment can represent a reservoir of antimicrobial resistance genes. In the present study, phenotypical, biochemical and molecular techniques were used to screen a collection of marine strains isolated in Italian aquaculture farms to investigate their beta-lactam resistance profiles. The genome of 12 carbapenemase and/or beta-lactamase producing strains was sequenced and a phylogenetic analysis of the beta-lactamases found in their chromosomes was performed. Gene annotation and prediction revealed the presence of blaAmpC and blaOXA-55-like in all the Shewanella algae isolates whereas in Vibrio anguillarum and Vibrio parahaemolyticus strains, blaAmpC and blaCARB-19 were found, respectively. Multiple alignments of OXA-55-like and AmpC protein sequences showed different point mutations. Finally, comparisons between enzyme phylogeny and strain clusterization based on sampling sites and dates indicate the diffusion of specific Multi Drug Resistant (MDR) Shewanella algae clones along the Italian Adriatic coast. © 2020 Elsevier Ltd
英文关键词	Antimicrobial resistance; Aquaculture; Beta-lactamases; Public health; Shewanellae; Vibrios
语种	英语
scopus关键词	Algae; Aquaculture; Genes; Health risks; Microorganisms; Public health; Antibiotic-resistant genes; Antimicrobial resistances; Aquatic environments; Lactamases; Phylogenetic analysis; Shewanellae; Vibrio parahaemolyticus; Vibrios; Strain; amoxicillin; amoxicillin plus clavulanic acid; antibiotic agent; aztreonam; bacterial protein; beta lactam antibiotic; beta lactamase; beta lactamase AmpC; carbapenemase; cefalotin; cefepime; cefotaxime; cefoxitin; ceftazidime; chloramphenicol; colistin; cotrimoxazole; ertapenem; fosfomycin; imipenem; meropenem; piperacillin; piperacillin plus tazobactam; protein OXA 55; sulfonamide; temocillin; ticarcillin; timentin; tobramycin; unclassified drug; antiinfective agent; beta lactamase; antibiotic resistance; aquaculture; bacterium; enzyme; gene; genomics; health risk; phylogeny; public health; antibiotic resistance; antibiotic resistance gene; aquaculture; Article; bacterial chromosome; bacterial genome; bacterial strain; bacterium isolate; bacterium isolation; controlled study; gene; gene sequence; health hazard; Italy; nonhuman; phenotype; phylogeny; point mutation; Shewanella; Shewanella algae; Vibrio; Vibrio anguillarum; Vibrio parahaemolyticus; antibiotic resistance; bacterial gene; environmental exposure; genetics; human; microbial sensitivity test; Shewanella; Adriatic Coast [Italy]; Italy; Listonella anguillarum; Shewanella algae; Vibrio; Vibrio parahaemolyticus; Anti-Bacterial Agents; Aquaculture; beta-Lactamases; Drug Resistance, Bacterial; Environmental Exposure; Genes, Bacterial; Humans; Italy; Microbial Sensitivity Tests; Phylogeny; Shewanella; Vibrio
来源期刊	Marine Pollution Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/149070
作者单位	Department of Diagnostics and Public Health, University of Verona, Italy; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy
推荐引用方式 GB/T 7714	Zago V.,Veschetti L.,Patuzzo C.,et al. Shewanella algae and Vibrio spp. strains isolated in Italian aquaculture farms are reservoirs of antibiotic resistant genes that might constitute a risk for human health[J],2020,154.
APA	Zago V.,Veschetti L.,Patuzzo C.,Malerba G.,&Lleo M.M..(2020).Shewanella algae and Vibrio spp. strains isolated in Italian aquaculture farms are reservoirs of antibiotic resistant genes that might constitute a risk for human health.Marine Pollution Bulletin,154.
MLA	Zago V.,et al."Shewanella algae and Vibrio spp. strains isolated in Italian aquaculture farms are reservoirs of antibiotic resistant genes that might constitute a risk for human health".Marine Pollution Bulletin 154(2020).