气候变化领域集成服务门户(CCPortal): Molecularly imprinted polymer solid phase extraction coupled with liquid chromatography-high resolution mass spectrometry for the detection of gonyautoxins 2&3 in seawater

CCPortal

DOI	10.1016/j.marpolbul.2020.111333
	Molecularly imprinted polymer solid phase extraction coupled with liquid chromatography-high resolution mass spectrometry for the detection of gonyautoxins 2&3 in seawater
	Zhang Y.; Qu J.; Du W.; Wu M.; Liu L.
发表日期	2020
ISSN	0025326X
卷号	157
英文摘要	Paralytic shellfish toxins (PSTs) cause risks to human health through food chains. Understanding the change of PSTs in seawater is critical for predicting the safety of seafood. Most reported methods for the detection of PSTs in microalgae or shellfish are not applicable in seawater because of extremely low concentration and matrix interferences. High resolution mass spectrometry (HRMS), quadrupole exactive orbitrap detects molecular ions accurately, and molecularly imprinted solid-phase extraction (MISPE) is recognized effective to reduce the matrix interference. GTXs 2&3 are two of common marine toxins in PSTs. In this study, a sensitive method consisting MISPE and liquid chromatography LC-HRMS was developed for the detection of GTXs 2&3 with a limit of detection (LOD) of 47.4 ng/L in seawater. With this method, samples obtained from the estuaries of the Shuangtaizi and Daliao Rivers were analyzed, and the results indicated the concentrations were lower than LOD in the area under investigation. © 2020 Elsevier Ltd
英文关键词	Gonyautoxins 2&3; LC-HRMS; Liaodong Bay; Molecularly imprinted solid-phase extraction; Seawater sample
语种	英语
scopus关键词	Health risks; Liquid chromatography; Mass spectrometry; Phase separation; Seawater; High resolution mass spectrometry; Limit of detection; Liquid chromatography-high resolution mass spectrometries; Matrix interference; Molecularly Imprinted Polymer; Molecularly imprinted solid-phase extraction; Paralytic shellfish toxins; Solid-phase extraction; Extraction; gonyautoxin; polymer; sea water; gonyautoxins; saxitoxin; sea water; concentration (composition); detection method; extraction method; liquid chromatography; mass spectrometry; microalga; molecular analysis; polymer; shellfish; toxic organism; alga; Article; chemical analysis; estuary; limit of detection; liquid chromatography-mass spectrometry; measurement accuracy; molecular imprinting; nonhuman; solid phase extraction; water sampling; high performance liquid chromatography; human; liquid chromatography; mass spectrometry; solid phase extraction; China; Daliao Estuary; Liaoning; Shuangtai Estuary; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Mass Spectrometry; Molecular Imprinting; Polymers; Saxitoxin; Seawater; Solid Phase Extraction
来源期刊	Marine Pollution Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/148804
作者单位	School of Ocean Science and Technology, Dalian University of Technology, No. 2 Dagong Road, Panjin, Liaoning 124221, China
推荐引用方式 GB/T 7714	Zhang Y.,Qu J.,Du W.,et al. Molecularly imprinted polymer solid phase extraction coupled with liquid chromatography-high resolution mass spectrometry for the detection of gonyautoxins 2&3 in seawater[J],2020,157.
APA	Zhang Y.,Qu J.,Du W.,Wu M.,&Liu L..(2020).Molecularly imprinted polymer solid phase extraction coupled with liquid chromatography-high resolution mass spectrometry for the detection of gonyautoxins 2&3 in seawater.Marine Pollution Bulletin,157.
MLA	Zhang Y.,et al."Molecularly imprinted polymer solid phase extraction coupled with liquid chromatography-high resolution mass spectrometry for the detection of gonyautoxins 2&3 in seawater".Marine Pollution Bulletin 157(2020).