气候变化领域集成服务门户(CCPortal): A tensile ring drives tissue flows to shape the gastrulating amniote embryo

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DOI	10.1126/science.aaw1965
	A tensile ring drives tissue flows to shape the gastrulating amniote embryo
	Saadaoui M.; Rocancourt D.; Roussel J.; Corson F.; Gros J.
发表日期	2020
ISSN	0036-8075
起始页码	453
结束页码	458
卷号	367 期号:6476
英文摘要	Tissue morphogenesis is driven by local cellular deformations that are powered by contractile actomyosin networks. How localized forces are transmitted across tissues to shape them at a mesoscopic scale is still unclear. Analyzing gastrulation in entire avian embryos, we show that it is driven by the graded contraction of a large-scale supracellular actomyosin ring at the margin between the embryonic and extraembryonic territories. The propagation of these forces is enabled by a fluid-like response of the epithelial embryonic disk, which depends on cell division. A simple model of fluid motion entrained by a tensile ring quantitatively captures the vortex-like “polonaise” movements that accompany the formation of the primitive streak. The geometry of the early embryo thus arises from the transmission of active forces generated along its boundary. Copyright © 2020 The Authors,
关键词	cell embryonic development fluid flow geometry morphogenesis article bird cell division embryo gastrulation geometry motion nonhuman primitive streak Aves
语种	英语
来源机构	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133768
推荐引用方式 GB/T 7714	Saadaoui M.,Rocancourt D.,Roussel J.,et al. A tensile ring drives tissue flows to shape the gastrulating amniote embryo[J]. Science,2020,367(6476).
APA	Saadaoui M.,Rocancourt D.,Roussel J.,Corson F.,&Gros J..(2020).A tensile ring drives tissue flows to shape the gastrulating amniote embryo.,367(6476).
MLA	Saadaoui M.,et al."A tensile ring drives tissue flows to shape the gastrulating amniote embryo".367.6476(2020).