气候变化领域集成服务门户(CCPortal): Enantioselective remote C-H activation directed by a chiral cation

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DOI	10.1126/science.aay9187
	Enantioselective remote C-H activation directed by a chiral cation
	Genov G.R.; Douthwaite J.L.; Lahdenperä A.S.K.; Gibson D.C.; Phipps R.J.
发表日期	2020
ISSN	0036-8075
起始页码	1246
结束页码	1251
卷号	367 期号:6483
英文摘要	Chiral cations have been used extensively as organocatalysts, but their application to rendering transition metal-catalyzed processes enantioselective remains rare. This is despite the success of the analogous charge-inverted strategy in which cationic metal complexes are paired with chiral anions. We report here a strategy to render a common bipyridine ligand anionic and pair its iridium complexes with a chiral cation derived from quinine. We have applied these ion-paired complexes to long-range asymmetric induction in the desymmetrization of the geminal diaryl motif, located on a carbon or phosphorus center, by enantioselective C-H borylation. In principle, numerous common classes of ligand could likewise be amenable to this approach. © 2020 American Association for the Advancement of Science. All rights reserved.
关键词	anion bipyridine carbon cation iridium phosphorus quinine carbon catalysis cation ligand phosphorus transition element Article borylation catalysis chemical bond chemical structure chirality enantioselectivity priority journal
语种	英语
来源机构	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133626
推荐引用方式 GB/T 7714	Genov G.R.,Douthwaite J.L.,Lahdenperä A.S.K.,et al. Enantioselective remote C-H activation directed by a chiral cation[J]. Science,2020,367(6483).
APA	Genov G.R.,Douthwaite J.L.,Lahdenperä A.S.K.,Gibson D.C.,&Phipps R.J..(2020).Enantioselective remote C-H activation directed by a chiral cation.,367(6483).
MLA	Genov G.R.,et al."Enantioselective remote C-H activation directed by a chiral cation".367.6483(2020).