气候变化领域集成服务门户(CCPortal): Facial expressions of emotion states and their neuronal correlates in mice

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DOI	10.1126/science.aaz9468
	Facial expressions of emotion states and their neuronal correlates in mice
	Dolensek N.; Gehrlach D.A.; Klein A.S.; Gogolla N.
发表日期	2020
ISSN	0036-8075
卷号	368 期号:6486
英文摘要	Understanding the neurobiological underpinnings of emotion relies on objective readouts of the emotional state of an individual, which remains a major challenge especially in animal models. We found that mice exhibit stereotyped facial expressions in response to emotionally salient events, as well as upon targeted manipulations in emotion-relevant neuronal circuits. Facial expressions were classified into distinct categories using machine learning and reflected the changing intrinsic value of the same sensory stimulus encountered under different homeostatic or affective conditions. Facial expressions revealed emotion features such as intensity, valence, and persistence. Two-photon imaging uncovered insular cortical neuron activity that correlated with specific facial expressions and may encode distinct emotions. Facial expressions thus provide a means to infer emotion states and their neuronal correlates in mice. © 2020 American Association for the Advancement of Science. All rights reserved.
关键词	gene expression learning machine learning nervous system rodent rodenticide animal experiment article brain cell controlled study facial expression machine learning male mouse nonhuman photon sensory stimulation Animalia Mus
语种	英语
来源机构	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133586
推荐引用方式 GB/T 7714	Dolensek N.,Gehrlach D.A.,Klein A.S.,et al. Facial expressions of emotion states and their neuronal correlates in mice[J]. Science,2020,368(6486).
APA	Dolensek N.,Gehrlach D.A.,Klein A.S.,&Gogolla N..(2020).Facial expressions of emotion states and their neuronal correlates in mice.,368(6486).
MLA	Dolensek N.,et al."Facial expressions of emotion states and their neuronal correlates in mice".368.6486(2020).