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DOI	10.1126/science.aba5901
	A dual light-driven palladium catalyst: Breaking the barriers in carbonylation reactions
	Torres G.M.; Liu Y.; Arndtsen B.A.
发表日期	2020
ISSN	0036-8075
起始页码	318
结束页码	323
卷号	368 期号:6488
英文摘要	Transition metal-catalyzed coupling reactions have become one of the most important tools in modern synthesis. However, an inherent limitation to these reactions is the need to balance operations, because the factors that favor bond cleavage via oxidative addition ultimately inhibit bond formation via reductive elimination. Here, we describe an alternative strategy that exploits simple visible-light excitation of palladium to drive both oxidative addition and reductive elimination with low barriers. Palladiumcatalyzed carbonylations can thereby proceed under ambient conditions, with challenging aryl or alkyl halides and difficult nucleophiles, and generate valuable carbonyl derivatives such as acid chlorides, esters, amides, or ketones in a now-versatile fashion. Mechanistic studies suggest that concurrent excitation of palladium(0) and palladium(II) intermediates is responsible for this activity. © 2020 American Association for the Advancement of Science. All rights reserved.
关键词	amide carbon monoxide chloride electrophile ester ketone nucleophile palladium catalyst chemical bonding chemical reaction light effect palladium Article blue light carbonylation catalysis catalyst chemical reaction controlled study electron transport environmental temperature light light absorption oxidative addition photoreactivity priority journal reductive elimination room temperature
语种	英语
来源机构	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133562
推荐引用方式 GB/T 7714	Torres G.M.,Liu Y.,Arndtsen B.A.. A dual light-driven palladium catalyst: Breaking the barriers in carbonylation reactions[J]. Science,2020,368(6488).
APA	Torres G.M.,Liu Y.,&Arndtsen B.A..(2020).A dual light-driven palladium catalyst: Breaking the barriers in carbonylation reactions.,368(6488).
MLA	Torres G.M.,et al."A dual light-driven palladium catalyst: Breaking the barriers in carbonylation reactions".368.6488(2020).