气候变化领域集成服务门户(CCPortal): Unexpected conservation and global transmission o agrobacterial virulence plasmids

CCPortal

DOI	10.1126/science.aba5256
	Unexpected conservation and global transmission o agrobacterial virulence plasmids
	Weisberg A.J.; Davis E.W.; II; Tabima J.; Belcher M.S.; Miller M.; Kuo C.-H.; Loper J.E.; Grünwald N.J.; Putnam M.L.; Chang J.H.
发表日期	2020
ISSN	0036-8075
卷号	368 期号:6495
英文摘要	The accelerated evolution and spread of pathogens are threats to host species. Agrobacteria require an oncogenic Ti or Ri plasmid to transfer genes into plants and cause disease. We developed a strategy to characterize virulence plasmids and applied it to analyze hundreds of strains collected between 1927 and 2017, on six continents and from more than 50 host species. In consideration of prior evidence for prolific recombination, it was surprising that oncogenic plasmids are descended from a few conserved lineages. Characterization of a hierarchy of features that promote or constrain plasticity allowed inference of the evolutionary history across the plasmid lineages. We uncovered epidemiological patterns that highlight the importance of plasmid transmission in pathogen diversification as well as in long-term persistence and the global spread of disease. © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works
关键词	epidemiology parasite transmission pathogen persistence plasticity plastid recombination virulence
语种	英语
来源机构	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133448
推荐引用方式 GB/T 7714	Weisberg A.J.,Davis E.W.,II,et al. Unexpected conservation and global transmission o agrobacterial virulence plasmids[J]. Science,2020,368(6495).
APA	Weisberg A.J..,Davis E.W..,II.,Tabima J..,Belcher M.S..,...&Chang J.H..(2020).Unexpected conservation and global transmission o agrobacterial virulence plasmids.,368(6495).
MLA	Weisberg A.J.,et al."Unexpected conservation and global transmission o agrobacterial virulence plasmids".368.6495(2020).