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| DOI | 10.1126/science.aba9411 |
| Measles virus and rinderpest virus divergence dated to the sixth century BCE | |
| Düx A.; Lequime S.; Patrono L.V.; Vrancken B.; Boral S.; Gogarten J.F.; Hilbig A.; Horst D.; Merkel K.; Prepoint B.; Santibanez S.; Schlotterbeck J.; Suchard M.A.; Ulrich M.; Widulin N.; Mankertz A.; Leendertz F.H.; Harper K.; Schnalke T.; Lemey P.; Calvignac-Spencer S. | |
| 发表日期 | 2020 |
| ISSN | 0036-8075 |
| 起始页码 | 1367 |
| 结束页码 | 1370 |
| 卷号 | 368期号:6497 |
| 英文摘要 | Many infectious diseases are thought to have emerged in humans after the Neolithic revolution. Although it is broadly accepted that this also applies to measles, the exact date of emergence for this disease is controversial. We sequenced the genome of a 1912 measles virus and used selection-aware molecular clock modeling to determine the divergence date of measles virus and rinderpest virus. This divergence date represents the earliest possible date for the establishment of measles in human populations. Our analyses show that the measles virus potentially arose as early as the sixth century BCE, possibly coinciding with the rise of large cities. © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works |
| 关键词 | divergenceinfectious diseasemeaslesmolecular analysisNeolithicvirusMeasles virusRinderpest viruscitycommunicable diseasegenetic variationgeneticshistoryhumanmeaslesMeasles virusmolecular evolutionRinderpest virusvirologyCitiesCommunicable Diseases, EmergingEvolution, MolecularGenetic VariationHistory, AncientHumansMeaslesMeasles virusRinderpest virus |
| 语种 | 英语 |
| 来源机构 | Science |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/133414 |
| 推荐引用方式 GB/T 7714 | Düx A.,Lequime S.,Patrono L.V.,et al. Measles virus and rinderpest virus divergence dated to the sixth century BCE[J]. Science,2020,368(6497). |
| APA | Düx A..,Lequime S..,Patrono L.V..,Vrancken B..,Boral S..,...&Calvignac-Spencer S..(2020).Measles virus and rinderpest virus divergence dated to the sixth century BCE.,368(6497). |
| MLA | Düx A.,et al."Measles virus and rinderpest virus divergence dated to the sixth century BCE".368.6497(2020). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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