气候变化领域集成服务门户(CCPortal): C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow

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DOI	10.1126/science.abb4688
	C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow
	Laudadio G.; Deng Y.; van der Wal K.; Ravelli D.; Nuño M.; Fagnoni M.; Guthrie D.; Sun Y.; Noël T.
发表日期	2020
ISSN	10959203
起始页码	92
结束页码	96
卷号	369 期号:6499
英文摘要	Direct activation of gaseous hydrocarbons remains a major challenge for the chemistry community. Because of the intrinsic inertness of these compounds, harsh reaction conditions are typically required to enable C(sp3)-H bond cleavage, barring potential applications in synthetic organic chemistry. Here, we report a general and mild strategy to activate C(sp3)-H bonds in methane, ethane, propane, and isobutane through hydrogen atom transfer using inexpensive decatungstate as photocatalyst at room temperature. The corresponding carbon-centered radicals can be effectively trapped by a variety of Michael acceptors, leading to the corresponding hydroalkylated adducts in good isolated yields and high selectivity (38 examples). Copyright © 2020, American Association for the Advancement of Science.
语种	英语
来源机构	Science (New York, N.Y.)
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133374
推荐引用方式 GB/T 7714	Laudadio G.,Deng Y.,van der Wal K.,et al. C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow[J]. Science (New York, N.Y.),2020,369(6499).
APA	Laudadio G..,Deng Y..,van der Wal K..,Ravelli D..,Nuño M..,...&Noël T..(2020).C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow.,369(6499).
MLA	Laudadio G.,et al."C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow".369.6499(2020).