气候变化领域集成服务门户(CCPortal): Modification by seasonal influenza and season on the association between ambient air pollution and child respiratory diseases in Shenzhen, China

CCPortal

DOI	10.1016/j.atmosenv.2020.117621
	Modification by seasonal influenza and season on the association between ambient air pollution and child respiratory diseases in Shenzhen, China
	Liao Y.; Sun J.; Qian Z.M.; Mei S.; Li Y.; Lu Y.; McMillin S.E.; Lin H.; Lang L.
发表日期	2020
ISSN	1352-2310
卷号	234
英文摘要	Objective: To quantify the acute effect of ambient air pollution on the risk of respiratory diseases in children in a Chinese subtropical city, and to investigate whether seasonal influenza and season could modify this association. Methods: A Generalized Additive Model was performed to evaluate the association between ambient air pollutants, including fine particulate matter (PM2.5), respirable particulate matter (PM10), ozone (O3), sulfur dioxide (SO2), and nitrogen dioxide (NO2), and children's hospital visits for respiratory diseases in Shenzhen, China. Potential effect modification was identified by stratified analysis in terms of seasonal influenza and seasons. The robustness of the results was assessed by sensitivity analyses. Results: A total of 2,569,021 hospital visits for respiratory diseases were recorded among children under 15 years old. We observed significant acute effects of air pollution, and the largest effects were observed during lag2 (two days after exposure) for PM2.5 [excess risk (ER) = 2.50% (95% CI: 1.88%, 3.12%)], PM10 [ER = 1.79% (95% CI: 1.37%, 2.21%)], O3 [ER = 0.59% (95% CI: 0.23%, 0.95%)], and SO2 [ER = 7.84% (95% CI: 5.17%, 10.58%)], and during lag0 (day of exposure) for NO2 [ER = 2.39% (95% CI: 1.74%, 3.05%)]. Season modified these effects with stronger associations being observed during the cold season. Seasonal influenza modified the effects of particulate matters towards stronger association during seasonal influenza epidemic, but this modification was not statistically significant. Conclusion: Ambient air pollutants, specifically PM2.5, PM10, O3, SO2, and NO2, were significantly associated with increased child hospital visits for respiratory diseases in Shenzhen, China. The vulnerable windows for these effects were the cold season and seasonal influenza epidemics. © 2020 Elsevier Ltd
英文关键词	Air pollution; China; Effect modifier; Influenza; Respiratory disease; Season
语种	英语
scopus关键词	Air pollution; Hospitals; Nitrogen oxides; Pulmonary diseases; Sensitivity analysis; Sulfur dioxide; Ambient air pollution; Fine particulate matter (PM2.5); Generalized additive model; Influenza epidemics; Nitrogen dioxides; Particulate Matter; Respirable particulate matters; Stratified analysis; Particles (particulate matter); nitrogen dioxide; ozone; sulfur dioxide; ambient air; atmospheric pollution; child health; epidemic; influenza; ozone; particulate matter; pollution exposure; sensitivity analysis; sulfur dioxide; adolescent; air pollution; ambient air; Article; child; China; environmental exposure; human; particulate matter; priority journal; respiratory tract disease; risk assessment; season; seasonal influenza; China; Guangdong; Shenzhen
来源期刊	Atmospheric Environment
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/129434
作者单位	Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China; Department of Epidemiology and Biostatistics, College for Public Health & Social Justice, Saint Louis University, St. Louis, MO, United States; School of Social Work, College for Public Health & Social Justice, Saint Louis University, St. Louis, MO, United States; Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, China
推荐引用方式 GB/T 7714	Liao Y.,Sun J.,Qian Z.M.,et al. Modification by seasonal influenza and season on the association between ambient air pollution and child respiratory diseases in Shenzhen, China[J],2020,234.
APA	Liao Y..,Sun J..,Qian Z.M..,Mei S..,Li Y..,...&Lang L..(2020).Modification by seasonal influenza and season on the association between ambient air pollution and child respiratory diseases in Shenzhen, China.Atmospheric Environment,234.
MLA	Liao Y.,et al."Modification by seasonal influenza and season on the association between ambient air pollution and child respiratory diseases in Shenzhen, China".Atmospheric Environment 234(2020).