气候变化领域集成服务门户(CCPortal): Bioenergetic theory predicts infection dynamics of human schistosomes in intermediate host snails across ecological gradients

CCPortal

DOI	10.1111/ele.12937
	Bioenergetic theory predicts infection dynamics of human schistosomes in intermediate host snails across ecological gradients
	Civitello D.J.; Fatima H.; Johnson L.R.; Nisbet R.M.; Rohr J.R.
发表日期	2018
ISSN	1461023X
卷号	21 期号:5
英文摘要	Epidemiological dynamics depend on the traits of hosts and parasites, but hosts and parasites are heterogeneous entities that exist in dynamic environments. Resource availability is a particularly dynamic and potent environmental driver of within-host infection dynamics (temporal patterns of growth, reproduction, parasite production and survival). We developed, parameterised and validated a model for resource-explicit infection dynamics by incorporating a parasitism module into dynamic energy budget theory. The model mechanistically explained the dynamic multivariate responses of the human parasite Schistosoma mansoni and its intermediate host snail to variation in resources and host density. At the population level, feedbacks mediated by resource competition could create a unimodal relationship between snail density and human risk of exposure to schistosomes. Consequently, weak snail control could backfire if reductions in snail density release remaining hosts from resource competition. If resource competition is strong and relevant to schistosome production in nature, it could inform control strategies. © 2018 John Wiley & Sons Ltd/CNRS
英文关键词	Density dependence; energy budget; parasite production; parasitism; reproduction; resources
语种	英语
scopus关键词	Gastropoda; Schistosoma; Schistosoma mansoni; animal; Biomphalaria; energy metabolism; host parasite interaction; human; parasitology; Schistosoma mansoni; snail; Animals; Biomphalaria; Energy Metabolism; Host-Parasite Interactions; Humans; Schistosoma mansoni; Snails
来源期刊	Ecology Letters
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/121330
作者单位	Department of Biology, Emory University, 1510 Clifton Rd NE, Atlanta, GA 30322, United States; Global Health Institute, Duke University, Durham, NC, United States; Department of Statistics, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States; Department of Ecology, Evolution, and Marine Biology, University of California, Santa Barbara, UCSB, Santa Barbara, CA 93106, United States; Department of Integrative Biology, University of South Florida, 4202, East Fowler Ave., Tampa, FL 33620, United States
推荐引用方式 GB/T 7714	Civitello D.J.,Fatima H.,Johnson L.R.,et al. Bioenergetic theory predicts infection dynamics of human schistosomes in intermediate host snails across ecological gradients[J],2018,21(5).
APA	Civitello D.J.,Fatima H.,Johnson L.R.,Nisbet R.M.,&Rohr J.R..(2018).Bioenergetic theory predicts infection dynamics of human schistosomes in intermediate host snails across ecological gradients.Ecology Letters,21(5).
MLA	Civitello D.J.,et al."Bioenergetic theory predicts infection dynamics of human schistosomes in intermediate host snails across ecological gradients".Ecology Letters 21.5(2018).