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DOI	10.1016/j.atmosenv.2020.117355
	Characteristics and potential inhalation exposure risks of PM2.5–bound environmental persistent free radicals in Nanjing, a mega–city in China
	Guo X.; Zhang N.; Hu X.; Huang Y.; Ding Z.; Chen Y.; Lian H.-Z.
发表日期	2020
ISSN	13522310
卷号	224
英文摘要	PM2.5–bound toxic elements and organic pollutants have been extensively investigated, while limited information is available for environmental persistent free radicals (EPFRs) associated with PM2.5, which may lead to oxidative stress in the human lung when exposed to PM2.5. In this study, the levels and types of PM2.5–bound EPFRs present in Nanjing, a mega–city in China, were analyzed. PM2.5–bound EPFRs were found to mainly be a mixture of carbon– and oxygen–centered radicals. The concentration of PM2.5–bound EPFRs ranged from 2.78 × 1012 to 1.72 × 1013 spins m−3, with an average value of 7.61 × 1012 spins m−3. The half–life of the PM2.5–bound EPFRs was calculated to be an average of 83.5 days when stored at room temperature, with only weak correlations observed between EPFRs and conventional air pollutants (NO2, O3, CO and PM2.5)/PM2.5–bound transition metals (Cu, Zn, Cr, Mn, V, Cd, and Ni) and significant correlations between EPFRs and SO2/PM2.5–bound Fe. PM2.5–bound EPFRs can induce the formation of reactive oxygen species (ROS) in both water and a H2O2 solution, which are used to simulate lung solution of a healthy person and patient, respectively. Therefore, PM2.5–bound EPFRs can lead to potential oxidative stress in humans. Overall, PM2.5–bound EPFRs show an obvious temporal variation and can pose potential health risks to humans via the induction of ROS in the lung solution. © 2020 Elsevier Ltd
英文关键词	Half–life; Inhalation exposure; Oxidative stress; Reactive oxygen species; Temporal variation
语种	英语
来源期刊	Atmospheric Environment
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/120716
作者单位	State Key Laboratory of Analytical Chemistry for Life Science, Centre of Materials Analysis and School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China; School of Environmental Science & Engineering, Nanjing Tech University, 30 Puzhu Southern Road, Nanjing, 211816, China
推荐引用方式 GB/T 7714	Guo X.,Zhang N.,Hu X.,等. Characteristics and potential inhalation exposure risks of PM2.5–bound environmental persistent free radicals in Nanjing, a mega–city in China[J],2020,224.
APA	Guo X..,Zhang N..,Hu X..,Huang Y..,Ding Z..,...&Lian H.-Z..(2020).Characteristics and potential inhalation exposure risks of PM2.5–bound environmental persistent free radicals in Nanjing, a mega–city in China.Atmospheric Environment,224.
MLA	Guo X.,et al."Characteristics and potential inhalation exposure risks of PM2.5–bound environmental persistent free radicals in Nanjing, a mega–city in China".Atmospheric Environment 224(2020).