气候变化领域集成服务门户(CCPortal): Natural alleles of a proteasome alpha 2 subunit gene contribute to thermotolerance and adaptation of African rice

CCPortal

DOI	10.1038/ng.3305
	Natural alleles of a proteasome alpha 2 subunit gene contribute to thermotolerance and adaptation of African rice
	Li, Xin-Min; Chao, Dai-Yin; Wu, Yuan; Huang, Xuehui; Chen, Ke; Cui, Long-Gang; Su, Lei; Ye, Wang-Wei; Chen, Hao; Chen, Hua-Chang; Dong, Nai-Qian; Guo, Tao; Shi, Min; Feng, Qi; Zhang, Peng; Han, Bin; Shan, Jun-Xiang; Gao, Ji-Ping; Lin, Hong-Xuan
发表日期	2015
ISSN	1061-4036
EISSN	1546-1718
卷号	47 期号:7
英文摘要	Global warming threatens many aspects of human life(1,2), for example, by reducing crop yields(3-5). Breeding heat-tolerant crops using genes conferring thermotolerance is a fundamental way to help deal with this challenge(4-9). Here we identify a major quantitative trait locus (QTL) for thermotolerance in African rice (Oryza glaberrima), Thermo-tolerance 1 (TT1), which encodes an alpha 2 subunit of the 26S proteasome involved in the degradation of ubiquitinated proteins. Ubiquitylome analysis indicated that OgTT1 protects cells from heat stress through more efficient elimination of cytotoxic denatured proteins and more effective maintenance of heat-response processes than achieved with OsTT1. Variation in TT1 has been selected for on the basis of climatic temperature and has had an important role in local adaptation during rice evolution. In addition, we found that overexpression of OgTT1 was associated with markedly enhanced thermotolerance in rice, Arabidopsis and Festuca elata. This discovery may lead to an increase in crop security in the face of the ongoing threat of global warming.
学科领域	Genetics & Heredity
语种	英语
WOS研究方向	Genetics & Heredity
来源期刊	NATURE GENETICS
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/111809
作者单位	Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Plant Physiol & Ecol, Natl Key Lab Plant Mol Genet, Shanghai, Peoples R China
推荐引用方式 GB/T 7714	Li, Xin-Min,Chao, Dai-Yin,Wu, Yuan,et al. Natural alleles of a proteasome alpha 2 subunit gene contribute to thermotolerance and adaptation of African rice[J]. 中国科学院西北生态环境资源研究院,2015,47(7).
APA	Li, Xin-Min.,Chao, Dai-Yin.,Wu, Yuan.,Huang, Xuehui.,Chen, Ke.,...&Lin, Hong-Xuan.(2015).Natural alleles of a proteasome alpha 2 subunit gene contribute to thermotolerance and adaptation of African rice.NATURE GENETICS,47(7).
MLA	Li, Xin-Min,et al."Natural alleles of a proteasome alpha 2 subunit gene contribute to thermotolerance and adaptation of African rice".NATURE GENETICS 47.7(2015).