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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis  
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Desdín-Micó G.;  Soto-Heredero G.;  Aranda J.F.;  Oller J.;  Carrasco E.;  Gabandé-Rodríguez E.;  Blanco E.M.;  Alfranca A.;  Cussó L.;  Desco M.;  Ibañez B.;  Gortazar A.R.;  Fernández-Marcos P.;  Navarro M.N.;  Hernaez B.;  Alcamí A.;  Baixauli F.;  Mittelbrunn M.
收藏  |  浏览/下载：44/0  |  提交时间：2020/07/28
cardiovascular disease  enzyme activity  gene expression  metabolism  mitochondrial DNA  morbidity  senescence  tumor  Mus  DNA binding protein  mitochondrial protein  mitochondrial transcription factor A  nicotinamide adenine dinucleotide  transcription factor  tumor necrosis factor  animal  cytokine release syndrome  female  fitness  gene deletion  genetics  immunology  inflammation  longevity  male  metabolism  mitochondrion  mouse  multiple chronic conditions  mutant mouse strain  premature aging  T lymphocyte  ultrastructure  Aging, Premature  Animals  Cytokine Release Syndrome  DNA-Binding Proteins  Female  Gene Deletion  Inflammation  Longevity  Male  Mice  Mice, Mutant Strains  Mitochondria  Mitochondrial Proteins  Multimorbidity  NAD  Physical Fitness  T-Lymphocytes  Transcription Factors  Tumor Necrosis Factor-alpha