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Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Ebright R.Y.;  Lee S.;  Wittner B.S.;  Niederhoffer K.L.;  Nicholson B.T.;  Bardia A.;  Truesdell S.;  Wiley D.F.;  Wesley B.;  Li S.;  Mai A.;  Aceto N.;  Vincent-Jordan N.;  Szabolcs A.;  Chirn B.;  Kreuzer J.;  Comaills V.;  Kalinich M.;  Haas W.;  Ting D.T.;  Toner M.;  Vasudevan S.;  Haber D.A.;  Maheswaran S.;  Micalizzi D.S.
收藏  |  浏览/下载：60/0  |  提交时间：2020/07/28
CRISPR associated protein  epidermal growth factor receptor 2  Ki 67 antigen  ribosome protein  ribosome RNA  transcription factor E2F  ribosome protein  cancer  cell  gene expression  genetic engineering  protein  RNA  tumor  animal experiment  animal model  animal tissue  Article  biogenesis  bioluminescence  breast cancer  cell cycle progression  cell cycle regulation  cell proliferation  circulating tumor cell  controlled study  enzyme activation  epithelial mesenchymal transition  gene expression profiling  genetic transcription  human  human cell  lung metastasis  metastasis  microfluidics  mouse  nonhuman  overall survival  phenotype  priority journal  progression free survival  promoter region  protein expression  protein processing  protein synthesis  proteomics  RNA sequence  transcription regulation  animal  breast tumor  cancer transplantation  CRISPR Cas system  female  gene expression regulation  genetics  pathology  sequence analysis  tumor cell line  tumor embolism  Mus  Animals  Breast Neoplasms  Cell Line, Tumor  CRISPR-Cas Systems  Female  Gene Expression Regulation, Neoplastic  Humans  Mice  Neoplasm Metastasis  Neoplasm Transplantation  Neoplastic Cells, Circulating  Ribosomal Proteins  Sequence Analysis, RNA  
Partitioning of cancer therapeutics in nuclear condensates 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Klein I.A.;  Boija A.;  Afeyan L.K.;  Hawken S.W.;  Fan M.;  Dall'Agnese A.;  Oksuz O.;  Henninger J.E.;  Shrinivas K.;  Sabari B.R.;  Sagi I.;  Clark V.E.;  Platt J.M.;  Kar M.;  McCall P.M.;  Zamudio A.V.;  Manteiga J.C.;  Coffey E.L.;  Li C.H.;  Hannett N.M.;  Guo Y.E.;  Decker T.-M.;  Lee T.I.;  Zhang T.;  Weng J.-K.;  Taatjes D.J.;  Chakraborty A.;  Sharp P.A.;  Chang Y.T.;  Hyman A.A.;  Gray N.S.;  Young R.A.
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/28
cancer  condensate  disease  drug  physicochemical property  protein  tumor  antineoplastic agent  BRD4 protein, human  cell cycle protein  green fluorescent protein  heterochromatin-specific nonhistone chromosomal protein HP-1  MED1 protein, human  nonhistone protein  nuclear protein  nucleophosmin  peroxisome proliferator activated receptor binding protein  recombinant protein  serine arginine rich splicing factor  SRSF2 protein, human  transcription factor  cell nucleus  drug resistance  genetics  human  metabolism  neoplasm  Antineoplastic Agents  Cell Cycle Proteins  Cell Nucleus  Chromosomal Proteins, Non-Histone  Drug Resistance, Neoplasm  Green Fluorescent Proteins  Humans  Mediator Complex Subunit 1  Neoplasms  Nuclear Proteins  Recombinant Proteins  Serine-Arginine Splicing Factors  Transcription Factors