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| Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者: Guthrie L.M.; Soma S.; Yuan S.; Silva A.; Zulkifli M.; Snavely T.C.; Greene H.F.; Nunez E.; Lynch B.; de Ville C.; Shanbhag V.; Lopez F.R.; Acharya A.; Petris M.J.; Kim B.-E.; Gohil V.M.; Sacchettini J.C.
  收藏 | 浏览/下载：44/0 | 提交时间：2020/07/28
copper copper zinc superoxide dismutase cytochrome c oxidase dopamine beta monooxygenase elesclomol monophenol monooxygenase protein lysine 6 oxidase copper cytochrome c oxidase elesclomol hydrazine derivative copper cytochrome enzyme enzyme activity mitochondrion mortality mutation pathology rodent survival animal cell animal experiment animal model animal tissue Article cohort analysis controlled study disease severity drug mechanism Golgi complex H9c2(2-1) cell line in vivo study male Menkes syndrome mitochondrial dynamics mortality rate mouse nerve degeneration nonhuman priority journal secretory pathway survival rate animal brain cell line degenerative disease disease model drug effect genetics knockout mouse Menkes syndrome metabolism mitochondrion pathology rat transport at the cellular level Murinae Mus Animals Biological Transport Brain Cell Line Copper Copper Transporter 1 Disease Models, Animal Electron Transport Complex IV Hydrazines Male Menkes Kinky Hair Syndrome Mice Mice, Knockout Mitochondria Neurodegenerative Diseases Rats |
| Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者: Uckelmann H.J.; Kim S.M.; Wong E.M.; Hatton C.; Giovinazzo H.; Gadrey J.Y.; Krivtsov A.V.; Rücker F.G.; Döhner K.; McGeehan G.M.; Levine R.L.; Bullinger L.; Vassiliou G.S.; Armstrong S.A.
收藏 | 浏览/下载：41/0 | 提交时间：2020/07/28
antileukemic agent methionine unclassified drug vtp 50469 biological development cancer cell disease treatment mutation numerical model oral health acute myeloid leukemia animal cell animal experiment animal model antineoplastic activity Article cell proliferation cell self-renewal chromatin controlled study drug targeting gene gene mutation leukemia cell molecularly targeted therapy mouse mouse model nonhuman NPM1 gene preleukemia priority journal Mus |
| A genetic mechanism for sexual dichromatism in birds 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Gazda M.A.; Araújo P.M.; Lopes R.J.; Toomey M.B.; Andrade P.; Afonso S.; Marques C.; Nunes L.; Pereira P.; Trigo S.; Hill G.E.; Corbo J.C.; Carneiro M.
收藏 | 浏览/下载：53/0 | 提交时间：2020/07/28
carotenoid color morph enzyme activity genetic analysis hybrid molecular analysis ornamentation phenotype physiological response sexual dimorphism sexual selection Aves Carduelis cucullata Fringillidae carotenoid dioxygenase transcriptome anatomy and histology animal evolution female finch genetics male metabolism physiology pigmentation Serinus sex factor sexual characteristics Animals Biological Evolution Canaries Carotenoids Dioxygenases Female Finches Male Pigmentation Sex Characteristics Sex Factors Transcriptome |
| Soil quality and mesofauna diversity relationship are modulated by woody species and seasonality in semiarid oak forest 期刊论文
, 2020, 卷号: 473
作者: Heydari M.; Eslaminejad P.; Kakhki F.V.; Mirab-balou M.; Omidipour R.; Prévosto B.; Kooch Y.; Lucas-Borja M.E.
收藏 | 浏览/下载：38/0 | 提交时间：2020/07/28
Amplitude modulation Arid regions Forestry Nitrogen Organic carbon Soil quality Springs (components) Available potassiums Biological characteristic Chemical and biologicals Conservation projects Microbial biomass carbon Shannon-wiener diversity indices Soil chemical property Substrate-induced respirations Soil conservation bioindicator biomass deciduous forest deciduous tree diversity index microbial activity nitrogen seasonal variation seasonality semiarid region shrub soil biota soil organic matter soil quality species diversity woody plant Averages Chemical Properties Forestry Nitrogen Quality Shrubs Soil Trees Iran Acer monspessulanum Arthropoda Crataegus Lonicera Piper methysticum Pistacia atlantica Prunus Quercus brantii Scoparia |
| Size matters but is big always better? Effectiveness of urea and Phlebiopsis gigantea as treatment against Heterobasidion on Picea abies stumps of variable size 期刊论文
, 2020, 卷号: 462
作者: Blomquist M.; Larsson Herrera S.; Hofmann J.; Beram R.C.; Cleary M.; Rönnberg J.
收藏 | 浏览/下载：46/0 | 提交时间：2020/07/28
Metabolism Plants (botany) Urea Airborne infection Biological control agent Coniferous forests Northern Hemispheres Norway spruce stands Phlebiopsis gigantea Pre-commercial thinning Standard practices Forestry airborne survey biological control coniferous forest economic activity forest management fungal disease Northern Hemisphere stand structure thinning urea Diseases Felling Forestry Frequency Metabolism Processing Stumps Urea Sweden Heterobasidion Phlebiopsis gigantea Picea abies |
| Structure of V-ATPase from the mammalian brain 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者: Abbas Y.M.; Wu D.; Bueler S.A.; Robinson C.V.; Rubinstein J.L.
收藏 | 浏览/下载：40/0 | 提交时间：2020/07/28
adenosine triphosphatase neurotransmitter proton renin unclassified drug vacuolar type adenosine triphosphatase Atp6ap1 protein, rat ATP6AP2 protein, rat bacterial protein biological marker cell surface receptor proton transporting adenosine triphosphate synthase blood brain catalysis catalyst enzyme enzyme activity membrane protein Article axon blood pressure regulation brain tissue catalysis chemical structure cryoelectron microscopy electrolyte balance electron microscopy human hydrolysis Legionella pneumophila molecular docking nerve cell neurotransmitter uptake nonhuman priority journal protein structure signal transduction Wnt signaling yeast animal biocatalysis brain cell membrane chemical model chemistry enzymology protein domain rat renin angiotensin aldosterone system Legionella pneumophila Mammalia Rattus Animals Bacterial Proteins Biocatalysis Biomarkers Brain Cell Membrane Cryoelectron Microscopy Models, Chemical Protein Domains Rats Receptors, Cell Surface Renin-Angiotensin System Vacuolar Proton-Translocating ATPases Wnt Signaling Pathway |
| Characteristics and Distribution of efficient ice nucleating particles in rainwater and soil 期刊论文
, 2020, 卷号: 246
作者: Zhang S.; Du R.; Chen H.; Zhang Y.; Du P.; Ren W.
收藏 | 浏览/下载：41/0 | 提交时间：2020/07/28
Precipitation (meteorology) Soils Biological matter Biological particles Heat resistant High-throughput sequencing Hydrologic cycles Nucleating activity Precipitation events Warm temperatures Ice |
| Morphological and isotopic changes of heterocystous cyanobacteria in response to N 2 partial pressure 期刊论文
, 2019, 卷号: 17, 期号: 1
作者: Silverman S.N.; Kopf S.H.; Bebout B.M.; Gordon R.; Som S.M.
收藏 | 浏览/下载：33/0 | 提交时间：2020/07/28
atmospheric pressure barometry biological control cyanobacterium enzyme activity isotopic analysis morphology nitrogen fixation nitrogen isotope partial pressure photosynthesis Anabaena Anabaena cylindrica Anabaena variabilis Cyanobacteria nitrogen nitrogenase Anabaena enzymology metabolism nitrogen fixation partial pressure physiology Anabaena Nitrogen Fixation Nitrogen Isotopes Nitrogenase Partial Pressure |
| The kinetics of siderophore-mediated olivine dissolution 期刊论文
, 2019, 卷号: 17, 期号: 4
作者: Torres M.A.; Dong S.; Nealson K.H.; West A.J.
收藏 | 浏览/下载：37/0 | 提交时间：2020/07/28
alkalinity bioavailability dissolution immobilization ligand microbial activity olivine reaction kinetics secondary mineral siderophore silicate mineral iron derivative magnesium derivative olivine siderophore silicate biological model chemistry kinetics microflora physiology solubility Iron Compounds Kinetics Magnesium Compounds Microbiota Models, Biological Siderophores Silicates Solubility |
| Assessing soil biodiversity potentials in Europe 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2017, 卷号: 589, 页码: 236-249
作者: Aksoy, Ece; Louwagie, Geertrui; Gardi, Ciro; Gregor, Mirko; Schroeder, Christoph; Loehnertz, Manuel
收藏 | 浏览/下载：31/0 | 提交时间：2019/05/04
Soil functions Biodiversity pool Mapping Earthworms Biological activity Environmental variables |
