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Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Gilan O.;  Rioja I.;  Knezevic K.;  Bell M.J.;  Yeung M.M.;  Harker N.R.;  Lam E.Y.N.;  Chung C.;  Bamborough P.;  Petretich M.;  Urh M.;  Atkinson S.J.;  Bassil A.K.;  Roberts E.J.;  Vassiliadis D.;  Burr M.L.;  Preston A.G.S.;  Wellaway C.;  Werner T.;  Gray J.R.;  Michon A.-M.;  Gobbetti T.;  Kumar V.;  Soden P.E.;  Haynes A.;  Vappiani J.;  Tough D.F.;  Taylor S.;  Dawson S.-J.;  Bantscheff M.;  Lindon M.;  Drewes G.;  Demont E.H.;  Daniels D.L.;  Grandi P.;  Prinjha R.K.;  Dawson M.A.
收藏  |  浏览/下载：51/0  |  提交时间：2020/07/28
7 (3,5 dimethyl 4 isoxazolyl) 1,3 dihydro 8 methoxy 1 [1 (2 pyridinyl)ethyl] 2h imidazo[4,5 c]quinolin 2 one  apremilast  bromodomain and extraterminal domain protein 1  bromodomain and extraterminal domain protein 2  bromodomain inhibitor  gsk 046  gsk 620  gsk 778  transcription factor  unclassified drug  cancer  drug  gene expression  immune response  inhibitor  physiological response  acute myeloid leukemia  animal experiment  animal model  animal tissue  antibody response  antineoplastic activity  antiproliferative activity  apoptosis  Article  binding affinity  controlled study  crystal structure  drug design  drug efficacy  drug protein binding  drug selectivity  drug specificity  drug structure  drug targeting  gene expression  high throughput screening  human  human cell  IC50  immunomodulation  in vivo study  inflammation  K-562 cell line  malignant neoplasm  MDA-MB-453 cell line  MOLM-13 cell line  mouse  nonhuman  priority journal  psoriasis  
Fire weather drives daily area burned and observations of fire behavior in mountain pine beetle affected landscapes 期刊论文
Environmental Research Letters, 2020, 卷号: 15, 期号: 5
作者:  Hart S.J.;  Preston D.L.
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/08
Evaluating the efficacy and equity of environmental stopgap measures 期刊论文
Nature Sustainability, 2020, 卷号: 3, 期号: 7
作者:  Buck H.J.;  Martin L.J.;  Geden O.;  Kareiva P.;  Koslov L.;  Krantz W.;  Kravitz B.;  Noël J.;  Parson E.A.;  Preston C.J.;  Sanchez D.L.;  Scarlett L.;  Talati S.
收藏  |  浏览/下载：58/0  |  提交时间：2021/01/18
Habitat heterogeneity drives the host-diversity-begets-parasite-diversity relationship: evidence from experimental and field studies 期刊论文
Ecology letters, 2016, 卷号: 19, 期号: 7
作者:  Johnson P.T.;  Wood C.L.;  Joseph M.B.;  Preston D.L.;  Haas S.E.;  Springer Y.P.
收藏  |  浏览/下载：53/0  |  提交时间：2020/03/12