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Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Overview of the Rocket Experiment for Neutral Upwelling Sounding Rocket 2 (RENU2)
期刊论文
Geophysical Research Letters, 2020, 卷号: 47, 期号: 21
作者:
Lessard M.R.
;
Fritz B.
;
Sadler B.
;
Cohen I.
;
Kenward D.
;
Godbole N.
;
Clemmons J.H.
;
Hecht J.H.
;
Lynch K.A.
;
Harrington M.
;
Roberts T.M.
;
Hysell D.
;
Crowley G.
;
Sigernes F.
;
Syrjäsuo M.
;
Ellingson P.
;
Partamies N.
;
Moen J.
;
Clausen L.
;
Oksavik K.
;
Yeoman T.
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/03/01
Coldest Canadian Arctic communities face greatest reductions in shorefast sea ice
期刊论文
Nature Climate Change, 2020, 卷号: 10, 期号: 6
作者:
Cooley S.W.
;
Ryan J.C.
;
Smith L.C.
;
Horvat C.
;
Pearson B.
;
Dale B.
;
Lynch A.H.
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/10/26
SealNet: A fully-automated pack-ice seal detection pipeline for sub-meter satellite imagery
期刊论文
Remote Sensing of Environment, 2020, 卷号: 239
作者:
Gonçalves B.C.
;
Spitzbart B.
;
Lynch H.J.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/05/24
An Integrated Framework for Ecological Drought across Riverscapes of North America
期刊论文
BIOSCIENCE, 2019, 卷号: 69, 期号: 6, 页码: 418-431
作者:
Kovach, Ryan P.
;
Dunham, Jason B.
;
Al-Chokhachy, Robert
;
Snyder, Craig D.
;
Letcher, Benjamin H.
;
Young, John A.
;
Beever, Erik A.
;
Pederson, Greg T.
;
Lynch, Abigail J.
;
Hitt, Nathaniel P.
;
Konrad, Chris P.
;
Jaeger, Kristin L.
;
Rea, Alan H.
;
Sepulveda, Adam J.
;
Lambert,
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/10/08
biodiversity
freshwater
vulnerability
monitoring
climate change
Exploring the lower thermal limits for development of the human malaria parasite, Plasmodium falciparum
期刊论文
BIOLOGY LETTERS, 2019, 卷号: 15, 期号: 6
作者:
Waite, Jessica L.
;
Suh, Eunho
;
Lynch, Penelope A.
;
Thomas, Matthew B.
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/10/08
pathogen
extrinsic incubation period
climate change
parasite infection
highlands
malaria risk
Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity
期刊论文
MICROBIOME, 2019, 卷号: 7
作者:
Tran, Tam T. T.
;
Cousin, Fabien J.
;
Lynch, Denise B.
;
Menon, Ravi
;
Brulc, Jennifer
;
Brown, Jillian R. -M.
;
O'
;
Herlihy, Eileen
;
Butto, Ludovica F.
;
Power, Katie
;
Jeffery, Ian B.
;
O'
;
Connor, Eibhlis M.
;
O'
;
Toole, Paul W.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/11/07
Dissolved Organic Matter Chemistry and Transport Along an Arctic Tundra Hillslope
期刊论文
GLOBAL BIOGEOCHEMICAL CYCLES, 2019, 卷号: 33, 期号: 1, 页码: 47-62
作者:
Lynch, Laurel M.
;
Machmuller, Megan B.
;
Boot, Claudia M.
;
Covino, Timothy P.
;
Rithner, Christopher D.
;
Cotrufo, M. Francesca
;
Hoyt, David W.
;
Wallenstein, Matthew D.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/11/07
Hurricane Sandy impacts on coastal wetland resilience
科技报告
报告编号: 70199531, , 2019
作者:
Cahoon, Donald R.
;
Olker, Jennifer H.
;
Yeates, Alice G.
;
Guntenspergen, Glenn R. glenn_guntenspergen@usgs.gov
;
Grace, James B. gracej@usgs.gov
;
Adamowicz, Susan C.
;
Anisfeld, Shimon C.
;
Baldwin, Andrew H.
;
Barrett, Nels
;
Beckett, Leah
;
Benzecry, Alice
;
Blum, Linda K.
;
Burdick, David M.
;
Crouch, William
;
Ekberg, Marci Cole
;
Fernald, Sarah
;
Grimes, Kristin Wilson
;
Grzyb, Joseph
;
Hartig, Ellen Kracauer
;
Kreeger, Danielle A.
;
Larson, Marit
;
Lerberg, Scott
;
Lynch, James C.
;
Maher, Nicole
;
Maxwell-Doyle, Martha
;
Mitchell, Laura R.
;
Mora, Jordan
;
O'Neill, Victoria
;
Padeletti, Angela
;
Prosser, Diann J. dprosser@usgs.gov
;
Quirk, Tracy
;
Raposa, Kenneth B.
;
Reay, William G.
;
Siok, Drexel
;
Snow, Christopher
;
Starke, Adam
;
Stevenson, J. Court
;
Staver, Lorie
;
Turner, Vincent
Adobe PDF(30894Kb)
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收藏
  |  
浏览/下载:79/24
  |  
提交时间:2019/11/06
LAGOS-NE: a multi-scaled geospatial and temporal database of lake ecological context and water quality for thousands of US lakes
期刊论文
GIGASCIENCE, 2017, 卷号: 6, 期号: 12
作者:
Soranno, Patricia A.
;
Bacon, Linda C.
;
Beauchene, Michael
;
Bednar, Karen E.
;
Bissell, Edward G.
;
Boudreau, Claire K.
;
Boyer, Marvin G.
;
Bremigan, Mary T.
;
Carpenter, Stephen R.
;
Carr, Jamie W.
;
Cheruvelil, Kendra S.
;
Christel, Samuel T.
;
Claucherty, Matt
;
Collins, Sarah M.
;
Conroy, Joseph D.
;
Downing, John A.
;
Dukett, Jed
;
Fergus, C. Emi
;
Filstrup, Christopher T.
;
Funk, Clara
;
Gonzalez, Maria J.
;
Green, Linda T.
;
Gries, Corinna
;
Halfman, John D.
;
Hamilton, Stephen K.
;
Hanson, Paul C.
;
Henry, Emily N.
;
Herron, Elizabeth M.
;
Hockings, Celeste
;
Jackson, James R.
;
Jacobson-Hedin, Kari
;
Janus, Lorraine L.
;
Jones, William W.
;
Jones, John R.
;
Keson, Caroline M.
;
King, Katelyn B. S.
;
Kishbaugh, Scott A.
;
Lapierre, Jean-Francois
;
Lathrop, Barbara
;
Latimore, Jo A.
;
Lee, Yuehlin
;
Lottig, Noah R.
;
Lynch, Jason A.
;
Matthews, Leslie J.
;
McDowell, William H.
;
Moore, Karen E. B.
;
Neff, Brian P.
;
Nelson, Sarah J.
;
Oliver, Samantha K.
;
Pace, Michael L.
;
Pierson, Donald C.
;
Poisson, Autumn C.
;
Pollard, Amina I.
;
Post, David M.
;
Reyes, Paul O.
;
Rosenberry, Donald O.
;
Roy, Karen M.
;
Rudstam, Lars G.
;
Sarnelle, Orlando
;
Schuldt, Nancy J.
;
Scott, Caren E.
;
Skaff, Nicholas K.
;
Smith, Nicole J.
;
Spinelli, Nick R.
;
Stachelek, Joseph J.
;
Stanley, Emily H.
;
Stoddard, John L.
;
Stopyak, Scott B.
;
Stow, Craig A.
;
Tallant, Jason M.
;
Tan, Pang-Ning
;
Thorpe, Anthony P.
;
Vanni, Michael J.
;
Wagner, Tyler
;
Watkins, Gretchen
;
Weathers, Kathleen C.
;
Webster, Katherine E.
;
White, Jeffrey D.
;
Wilmes, Marcy K.
;
Yuan, Shuai
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/05/04