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Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity 期刊论文
Science, 2021, 卷号: 373, 期号: 6555
作者:  Gobeil S.M.-C.;  Janowska K.;  McDowell S.;  Mansouri K.;  Parks R.;  Stalls V.;  Kopp M.F.;  Manne K.;  Li D.;  Wiehe K.;  Saunders K.O.;  Edwards R.J.;  Korber B.;  Haynes B.F.;  Henderson R.;  Acharya P.
收藏  |  浏览/下载:27/0  |  提交时间:2022/01/14
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth 期刊论文
Science, 2021, 卷号: 371, 期号: 6525
作者:  Roark R.S.;  Li H.;  Williams W.B.;  Chug H.;  Mason R.D.;  Gorman J.;  Wang S.;  Lee F.-H.;  Rando J.;  Bonsignori M.;  Hwang K.-K.;  Saunders K.O.;  Wiehe K.;  Moody M.A.;  Hraber P.T.;  Wagh K.;  Giorgi E.E.;  Russell R.M.;  Bibollet-Ruche F.;  Liu W.;  Connel J.;  Smith A.G.;  DeVoto J.;  Murphy A.I.;  Smith J.;  Ding W.;  Zhao C.;  Chohan N.;  Okumura M.;  Rosario C.;  Ding Y.;  Lindemuth E.;  Bauer A.M.;  Bar K.J.;  Ambrozak D.;  Chao C.W.;  Chuang G.-Y.;  Geng H.;  Lin B.C.;  Louder M.K.;  Nguyen R.;  Zhang B.;  Lewis M.G.;  Raymond D.D.;  Doria-Rose N.A.;  Schramm C.A.;  Douek D.C.;  Roederer M.;  Kepler T.B.;  Kelsoe G.;  Mascola J.R.;  Kwong P.D.;  Korber B.T.;  Harrison S.C.;  Haynes B.F.;  Hahn B.H.;  Shaw G.M.
收藏  |  浏览/下载:29/0  |  提交时间:2022/01/14
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Gilan O.;  Rioja I.;  Knezevic K.;  Bell M.J.;  Yeung M.M.;  Harker N.R.;  Lam E.Y.N.;  Chung C.;  Bamborough P.;  Petretich M.;  Urh M.;  Atkinson S.J.;  Bassil A.K.;  Roberts E.J.;  Vassiliadis D.;  Burr M.L.;  Preston A.G.S.;  Wellaway C.;  Werner T.;  Gray J.R.;  Michon A.-M.;  Gobbetti T.;  Kumar V.;  Soden P.E.;  Haynes A.;  Vappiani J.;  Tough D.F.;  Taylor S.;  Dawson S.-J.;  Bantscheff M.;  Lindon M.;  Drewes G.;  Demont E.H.;  Daniels D.L.;  Grandi P.;  Prinjha R.K.;  Dawson M.A.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
7 (3,5 dimethyl 4 isoxazolyl) 1,3 dihydro 8 methoxy 1 [1 (2 pyridinyl)ethyl] 2h imidazo[4,5 c]quinolin 2 one  apremilast  bromodomain and extraterminal domain protein 1  bromodomain and extraterminal domain protein 2  bromodomain inhibitor  gsk 046  gsk 620  gsk 778  transcription factor  unclassified drug  cancer  drug  gene expression  immune response  inhibitor  physiological response  acute myeloid leukemia  animal experiment  animal model  animal tissue  antibody response  antineoplastic activity  antiproliferative activity  apoptosis  Article  binding affinity  controlled study  crystal structure  drug design  drug efficacy  drug protein binding  drug selectivity  drug specificity  drug structure  drug targeting  gene expression  high throughput screening  human  human cell  IC50  immunomodulation  in vivo study  inflammation  K-562 cell line  malignant neoplasm  MDA-MB-453 cell line  MOLM-13 cell line  mouse  nonhuman  priority journal  psoriasis  
Impacts of experimental alteration of water table regime and vascular plant community composition on peat mercury profiles and methylmercury production 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 682, 页码: 611-622
作者:  Haynes, Kristine M.;  Kane, Evan S.;  Potvin, Lynette;  Lilleskov, Erik A.;  Kolka, Randall K.;  Mitchell, Carl P. J.
收藏  |  浏览/下载:32/0  |  提交时间:2019/10/08
Hg(II) methylation  Demethylation  Enriched mercury isotope  Soil  Climate change  Water table fluctuation  
The earliest direct evidence of mammoth hunting in Central Europe – The Kraków Spadzista site (Poland) 期刊论文
Quaternary Science Reviews, 2019, 卷号: 213
作者:  Wojtal P.;  Haynes G.;  Klimowicz J.;  Sobczyk K.;  Tarasiuk J.;  Wroński S.;  Wilczyński J.
收藏  |  浏览/下载:24/0  |  提交时间:2020/11/23
Mammoth hunting strategies during the Late Gravettian in Central Europe as determined from case studies of Milovice I (Czech Republic) and Kraków Spadzista (Poland) 期刊论文
Quaternary Science Reviews, 2019, 卷号: 223
作者:  Wilczyński J.;  Wojtal P.;  Oliva M.;  Sobczyk K.;  Haynes G.;  Klimowicz J.;  Lengyel G.
收藏  |  浏览/下载:15/0  |  提交时间:2020/11/23
A synthesis of three decades of hydrological research at Scotty Creek; NWT; Canada 期刊论文
Hydrology and Earth System Sciences, 2019, 卷号: 23, 期号: 4
作者:  Quinton W.;  Berg A.;  Braverman M.;  Carpino O.;  Chasmer L.;  Connon R.;  Craig J.;  Devoie E.;  Hayashi M.;  Haynes K.;  Olefeldt D.;  Pietroniro A.;  Rezanezhad F.;  Schincariol R.;  Sonnentag O.
收藏  |  浏览/下载:28/0  |  提交时间:2021/01/06
Representing Grasslands Using Dynamic Prognostic Phenology Based on Biological Growth Stages: 1. Implementation in the Simple Biosphere Model (SiB4) 期刊论文
Journal of Advances in Modeling Earth Systems, 2019, 卷号: 11, 期号: 12
作者:  Haynes K.D.;  Baker I.T.;  Denning A.S.;  Stöckli R.;  Schaefer K.;  Lokupitiya E.Y.;  Haynes J.M.
收藏  |  浏览/下载:27/0  |  提交时间:2020/12/08
Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018, 卷号: 38, 期号: 1, 页码: 275-282
作者:  Ward-Caviness, Cavin K.;  Kraus, William E.;  Blach, Colette;  Haynes, Carol S.;  Dowdy, Elaine;  Miranda, Marie Lynn;  Devlin, Robert;  Diaz-Sanchez, David;  Cascio, Wayne E.;  Mukerjee, Shaibal;  Stallings, Casson;  Smith, Luther A.;  Gregory, Simon G.;  Shah, Svati H.;  Neas, Lucas M.;  Hauser, Elizabeth R.
收藏  |  浏览/下载:50/0  |  提交时间:2019/05/04
A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic 期刊论文
PLOS ONE, 2017, 卷号: 12, 期号: 3
作者:  Ward-Caviness, Cavin K.;  Neas, Lucas M.;  Blach, Colette;  Haynes, Carol S.;  LaRocque-Abramson, Karen;  Grass, Elizabeth;  Dowdy, Z. Elaine;  Devlin, Robert B.;  Diaz-Sanchez, David;  Cascio, Wayne E.;  Miranda, Marie Lynn;  Gregory, Simon G.;  Shah, Svati H.;  Kraus, William E.;  Hauser, Elizabeth R.
收藏  |  浏览/下载:43/0  |  提交时间:2019/05/04