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Differentiating Pathway-Specific From Nonspecific Effects in High-Throughput Toxicity Data: A Foundation for Prioritizing Adverse Outcome Pathway Development 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 163, 期号: 2, 页码: 500-515
作者:  Fay, Kellie A.;  Villeneuve, Daniel L.;  Swintek, Joe;  Edwards, Stephen W.;  Nelms, Mark D.;  Blackwell, Brett R.;  Ankley, Gerald T.
收藏  |  浏览/下载:33/0  |  提交时间:2019/05/04
AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 343, 页码: 71-83
作者:  Pittman, Maureen E.;  Edwards, Stephen W.;  Ives, Cataia;  Mortensen, Holly M.
收藏  |  浏览/下载:29/0  |  提交时间:2019/05/04
A Case Study Application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) Frameworks to Facilitate the Integration of Human Health and Ecological End Points for Cumulative Risk Assessment (CRA) 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 卷号: 52, 期号: 2, 页码: 839-849
作者:  Hines, David E.;  Edwards, Stephen W.;  Conolly, Rory B.;  Jarabek, Annie M.
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
Association analysis identifies 65 new breast cancer risk loci 期刊论文
NATURE, 2017, 卷号: 551, 期号: 7678, 页码: 92-+
作者:  Michailidou, Kyriaki;  Lindstrom, Sara;  Dennis, Joe;  Beesley, Jonathan;  Hui, Shirley;  Kar, Siddhartha;  Lemacon, Audrey;  Soucy, Penny;  Glubb, Dylan;  Rostamianfar, Asha;  Bolla, Manjeet K.;  Wang, Qin;  Tyrer, Jonathan;  Dicks, Ed;  Lee, Andrew;  Wang, Zhaoming;  Allen, Jamie;  Keeman, Renske;  Eilber, Ursula;  French, Juliet D.;  Chen, Xiao Qing;  Fachal, Laura;  McCue, Karen;  McCart, Amy E.;  Reed, Amy E. McCart;  Ghoussaini, Maya;  Carroll, Jason S.;  Jiang, Xia;  Finucane, Hilary;  Adams, Marcia;  Adank, Muriel A.;  Ahsan, Habibul;  Aittomaki, Kristiina;  Anton-Culver, Hoda;  Antonenkova, Natalia N.;  Arndt, Volker;  Aronson, Kristan J.;  Arun, Banu;  Auer, Paul L.;  Bacot, Francois;  Barrdahl, Myrto;  Baynes, Caroline;  Beckmann, Matthias W.;  Behrens, Sabine;  Benitez, Javier;  Bermisheva, Marina;  Bernstein, Leslie;  Blomqvist, Carl;  Bogdanova, Natalia V.;  Bojesen, Stig E.;  Bonanni, Bernardo;  Borresen-Dale, Anne-Lise;  Brand, Judith S.;  Brauch, Hiltrud;  Brennan, Paul;  Brenner, Hermann;  Brinton, Louise;  Broberg, Per;  Brock, Ian W.;  Broeks, Annegien;  Brooks-Wilson, Angela;  Brucker, Sara Y.;  Bruening, Thomas;  Burwinkel, Barbara;  Butterbach, Katja;  Cai, Qiuyin;  Cai, Hui;  Caldes, Trinidad;  Canzian, Federico;  Carracedo, Angel;  Carter, Brian D.;  Castelao, Jose E.;  Chan, Tsun L.;  Cheng, Ting-Yuan David;  Chia, Kee Seng;  Choi, Ji-Yeob;  Christiansen, Hans;  Clarke, Christine L.;  Collee, Margriet;  Conroy, Don M.;  Cordina-Duverger, Emilie;  Cornelissen, Sten;  Cox, David G.;  Cox, Angela;  Cross, Simon S.;  Cunningham, Julie M.;  Czene, Kamila;  Daly, Mary B.;  Devilee, Peter;  Doheny, Kimberly F.;  Doerk, Thilo;  dos-Santos-Silva, Isabel;  Dumont, Martine;  Durcan, Lorraine;  Dwek, Miriam;  Eccles, Diana M.;  Ekici, Arif B.;  Eliassen, A. Heather;  Ellberg, Carolina;  Elvira, Mingajeva;  Engel, Christoph;  Eriksson, Mikael;  Fasching, Peter A.;  Figueroa, Jonine;  Flesch-Janys, Dieter;  Fletcher, Olivia;  Flyger, Henrik;  Fritschi, Lin;  Gaborieau, Valerie;  Gabrielson, Marike;  Gago-Dominguez, Manuela;  Gao, Yu-Tang;  Gapstur, Susan M.;  Garcia-Saenz, Jose A.;  Gaudet, Mia M.;  Georgoulias, Vassilios;  Giles, Graham G.;  Glendon, Gord;  Goldberg, Mark S.;  Goldgar, David E.;  Gonzalez-Neira, Anna;  Alnaes, Grethe I. Grenaker;  Grip, Mervi;  Gronwald, Jacek;  Grundy, Anne;  Guenel, Pascal;  Haeberle, Lothar;  Hahnen, Eric;  Haiman, Christopher A.;  Hakansson, Niclas;  Hamann, Ute;  Hamel, Nathalie;  Hankinson, Susan;  Harrington, Patricia;  Hart, Steven N.;  Hartikainen, Jaana M.;  Hartman, Mikael;  Hein, Alexander;  Heyworth, Jane;  Hicks, Belynda;  Hillemanns, Peter;  Ho, Dona N.;  Hollestelle, Antoinette;  Hooning, Maartje J.;  Hoover, Robert N.;  Hopper, John L.;  Hou, Ming-Feng;  Hsiung, Chia-Ni;  Huang, Guanmengqian;  Humphreys, Keith;  Ishiguro, Junko;  Ito, Hidemi;  Iwasaki, Motoki;  Iwata, Hiroji;  Jakubowska, Anna;  Janni, Wolfgang;  John, Esther M.;  Johnson, Nichola;  Jones, Kristine;  Jones, Michael;  Jukkola-Vuorinen, Arja;  Kaaks, Rudolf;  Kabisch, Maria;  Kaczmarek, Katarzyna;  Kang, Daehee;  Kasuga, Yoshio;  Kerin, Michael J.;  Khan, Sofia;  Khusnutdinova, Elza;  Kiiski, Johanna I.;  Kim, Sung-Won;  Knight, Julia A.;  Kosma, Veli-Matti;  Kristensen, Vessela N.;  Kruger, Ute;  Kwong, Ava;  Lambrechts, Diether;  Le Marchand, Loic;  Lee, Eunjung;  Lee, Min Hyuk;  Lee, Jong Won;  Lee, Chuen Neng;  Lejbkowicz, Flavio;  Li, Jingmei;  Lilyquist, Jenna;  Lindblom, Annika;  Lissowska, Jolanta;  Lo, Wing-Yee;  Loibl, Sibylle;  Long, Jirong;  Lophatananon, Artitaya;  Lubinski, Jan;  Luccarini, Craig;  Lux, Michael P.;  Ma, Edmond S. K.;  MacInnis, Robert J.;  Maishman, Tom;  Makalic, Enes;  Malone, Kathleen E.;  Kostovska, Ivana Maleva;  Mannermaa, Arto;  Manoukian, Siranoush;  Manson, Joann E.;  Margolin, Sara;  Mariapun, Shivaani;  Martinez, Maria Elena;  Matsuo, Keitaro;  Mavroudis, Dimitrios;  McKay, James;  McLean, Catriona;  Meijers-Heijboer, Hanne;  Meindl, Alfons;  Menendez, Primitiva;  Menon, Usha;  Meyer, Jeffery;  Miao, Hui;  Miller, Nicola;  Taib, Nur Aishah Mohd;  Muir, Kenneth;  Mulligan, Anna Marie;  Mulot, Claire;  Neuhausen, Susan L.;  Nevanlinna, Heli;  Neven, Patrick;  Nielsen, Sune F.;  Noh, Dong-Young;  Nordestgaard, Borge G.;  Norman, Aaron;  Olopade, Olufunmilayo I.;  Olson, Janet E.;  Olsson, Hakan;  Olswold, Curtis;  Orr, Nick;  Pankratz, V. Shane;  Park, Sue K.;  Park-Simon, Tjoung-Won;  Lloyd, Rachel;  Perez, Jose I. A.;  Peterlongo, Paolo;  Peto, Julian;  Phillips, Kelly-Anne;  Pinchev, Mila;  Plaseska-Karanfilska, Dijana;  Prentice, Ross;  Presneau, Nadege;  Prokofyeva, Darya;  Pugh, Elizabeth;  Pylkas, Katri;  Rack, Brigitte;  Radice, Paolo;  Rahman, Nazneen;  Rennert, Gadi;  Rennert, Hedy S.;  Rhenius, Valerie;  Romero, Atocha;  Romm, Jane;  Ruddy, Kathryn J.;  Ruediger, Thomas;  Rudolph, Anja;  Ruebner, Matthias;  Rutgers, Emiel J. T.;  Saloustros, Emmanouil;  Sandler, Dale P.;  Sangrajrang, Suleeporn;  Sawyer, Elinor J.;  Schmidt, Daniel F.;  Schmutzler, Rita K.;  Schneeweiss, Andreas;  Schoemaker, Minouk J.;  Schumacher, Fredrick;  Schuermann, Peter;  Scott, Rodney J.;  Scott, Christopher;  Seal, Sheila;  Seynaeve, Caroline;  Shah, Mitul;  Sharma, Priyanka;  Shen, Chen-Yang;  Sheng, Grace;  Sherman, Mark E.;  Shrubsole, Martha J.;  Shu, Xiao-Ou;  Smeets, Ann;  Sohn, Christof;  Southey, Melissa C.;  Spinelli, John J.;  Stegmaier, Christa;  Stewart-Brown, Sarah;  Stone, Jennifer;  Stram, Daniel O.;  Surowy, Harald;  Swerdlow, Anthony;  Tamimi, Rulla;  Taylor, Jack A.;  Tengstrom, Maria;  Teo, Soo H.;  Terry, Mary Beth;  Tessier, Daniel C.;  Thanasitthichai, Somchai;  Thoene, Kathrin;  Tollenaar, Rob A. E. M.;  Tomlinson, Ian;  Tong, Ling;  Torres, Diana;  Truong, Therese;  Tseng, Chiu-Chen;  Tsugane, Shoichiro;  Ulmer, Hans-Ulrich;  Ursin, Giske;  Untch, Michael;  Vachon, Celine;  van Asperen, Christi J.;  Van Den Berg, David;  van den Ouweland, Ans M. W.;  van der Kolk, Lizet;  van der Luijt, Rob B.;  Vincent, Daniel;  Vollenweider, Jason;  Waisfisz, Quinten;  Wang-Gohrke, Shan;  Weinberg, Clarice R.;  Wendt, Camilla;  Whittemore, Alice S.;  Wildiers, Hans;  Willett, Walter;  Winqvist, Robert;  Wolk, Alicja;  Wu, Anna H.;  Xia, Lucy;  Yamaji, Taiki;  Yang, Xiaohong R.;  Yip, Cheng Har;  Yoo, Keun-Young;  Yu, Jyh-Cherng;  Zheng, Wei;  Zheng, Ying;  Zhu, Bin;  Ziogas, Argyrios;  Ziv, Elad;  Lakhani, Sunil R.;  Antoniou, Antonis C.;  Droit, Arnaud;  Andrulis, Irene L.;  Amos, Christopher I.;  Couch, Fergus J.;  Pharoah, Paul D. P.;  Chang-Claude, Jenny;  Hall, Per;  Hunter, David J.;  Milne, Roger L.;  Garcia-Closas, Montserrat;  Schmidt, Marjanka K.;  Chanock, Stephen J.;  Dunning, Alison M.;  Edwards, Stacey L.;  Bader, Gary D.;  Chenevix-Trench, Georgia;  Simard, Jacques;  Kraft, Peter;  Easton, Douglas F.
收藏  |  浏览/下载:54/0  |  提交时间:2019/05/04
Negative Predictors of Carcinogenicity for Environmental Chemicals 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 155, 期号: 1, 页码: 157-169
作者:  Hill, Thomas, III;  Nelms, Mark D.;  Edwards, Stephen W.;  Martin, Matthew;  Judson, Richard;  Corton, J. Christopher;  Wood, Charles E.
收藏  |  浏览/下载:26/0  |  提交时间:2019/05/04
The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 11, 页码: 1671-1682
作者:  Cote, Ila;  Andersen, Melvin E.;  Ankley, Gerald T.;  Barone, Stanley;  Birnbaum, Linda S.;  Boekelheide, Kim;  Bois, FredericY.;  Burgoon, Lyle D.;  Chiu, Weihsueh A.;  Crawford-Brown, Douglas;  Crofton, Kevin M.;  DeVito, Michael;  Devlin, Robert B.;  Edwards, Stephen W.;  Guyton, Kathryn Z.;  Hattis, Dale;  Judson, Richard S.;  Knight, Derek;  Krewski, Daniel;  Lambert, Jason;  Maull, Elizabeth Anne;  Mendrick, Donna;  Paoli, Gregory M.;  Patel, Chirag Jagdish;  Perkins, Edward J.;  Poje, Gerald;  Portier, Christopher J.;  Rusyn, Ivan;  Schulte, Paul A.;  Simeonov, Anton;  Smith, Martyn T.;  Thayer, Kristina A.;  Thomas, Russell S.;  Thomas, Reuben;  Tice, Raymond R.;  Vandenberg, John J.;  Villeneuve, Daniel L.;  Wesselkamper, Scott;  Whelan, Maurice;  Whittaker, Christine;  White, Ronald;  Xia, Menghang;  Yauk, Carole;  Zeise, Lauren;  Zhao, Jay;  DeWoskin, Robert S.
收藏  |  浏览/下载:35/0  |  提交时间:2019/05/04
Expanding on Successful Concepts, Models, and Organization 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 17, 页码: 8921-8922
作者:  Teeguarden, Justin G.;  Tan, Yu-Mei;  Edwards, Stephen W.;  Leonard, Jeremy A.;  Anderson, Kim A.;  Corley, Richard A.;  Kile, Molly L.;  Simonich, Staci L. Massey;  Stone, David;  Tanguay, Robert L.;  Waters, Katrina M.;  Harper, Stacey. L.;  Williams, David E.
收藏  |  浏览/下载:50/0  |  提交时间:2019/05/04
Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 9, 页码: 4579-4586
作者:  Teeguarden, Justin G.;  Tan, Yu-Mei;  Edwards, Stephen W.;  Leonard, Jeremy A.;  Anderson, Kim A.;  Corley, Richard A.;  Kile, Molly L.;  Simonich, Staci M.;  Stone, David;  Tanguay, Robert L.;  Waters, Katrina M.;  Harper, Stacey L.;  Williams, David E.
收藏  |  浏览/下载:47/0  |  提交时间:2019/05/04
Integrating Publicly Available Data to Generate Computationally Predicted Adverse Outcome Pathways for Fatty Liver 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 150, 期号: 2, 页码: 510-520
作者:  Bell, Shannon M.;  Angrish, Michelle M.;  Wood, Charles E.;  Edwards, Stephen W.
收藏  |  浏览/下载:29/0  |  提交时间:2019/05/04
An integrative data mining approach to identifying adverse outcome pathway signatures 期刊论文
TOXICOLOGY, 2016, 卷号: 350, 页码: 49-61
作者:  Oki, Noffisat O.;  Edwards, Stephen W.
收藏  |  浏览/下载:29/0  |  提交时间:2019/05/04