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| Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 23 作者: Dai J.; Sanchez A.; Adam C.; Ranjha L.; Reginato G.; Chervy P.; Tellier-Lebegue C.; Andreani J.; Guérois R.; Ropars V.; Le Du M.-H.; Maloisel L.; Martini E.; Legrand P.; Thureau A.; Cejka P.; Borde V.; Charbonniera J.-B. 收藏  |  浏览/下载:50/0  |  提交时间:2021/11/25 |
| Mechanistic insights into the synergistic activation of the RXR–PXR heterodimer by endocrine disruptor mixtures 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 1 作者: Delfosse V.; Huet T.; Harrus D.; Granell M.; Bourguet M.; Gardia-Parège C.; Chiavarina B.; Grimaldi M.; Le Mével S.; Blanc P.; Huang D.; Gruszczyk J.; Demeneix B.; Cianférani S.; Fini J.-B.; Balaguer P.; Bourguet W. 收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24 |
| Biochemical insights into Paf1 complex-induced stimulation of Rad6/Bre1-mediated H2B monoubiquitination 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Chen F.; Liu B.; Guo L.; Ge X.; Feng W.; Li D.-F.; Zhou H.; Long J. 收藏  |  浏览/下载:20/0  |  提交时间:2022/02/22 |
| A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- And heterodimers 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Haubrich J.; Font J.; Quast R.B.; Goupil-Lamy A.; Scholler P.; Nevoltris D.; Acher F.; Chames P.; Rondard P.; Prézeau L.; Pin J.-P. 收藏  |  浏览/下载:21/0  |  提交时间:2022/02/22 |
| A predictive model for salt nanoparticle formation using heterodimer stability calculations 期刊论文 ATMOSPHERIC CHEMISTRY AND PHYSICS, 2021, 卷号: 21, 期号: 15 作者: Chee S.; Barsanti K.; Smith J.N.; Myllys N. 收藏  |  浏览/下载:96/0  |  提交时间:2022/01/18 |
| BMP heterodimers signal via distinct type I receptor class functions 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15 作者: Tajer B.; Dutko J.A.; Little S.C.; Mullins M.C. 收藏  |  浏览/下载:17/0  |  提交时间:2021/05/24 |
| Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3 作者: Guest J.D.; Wang R.; Elkholy K.H.; Chagas A.; Chao K.L.; Cleveland T.E.; Kim Y.C.; Keck Z.-Y.; Marin A.; Yunus A.S.; Mariuzza R.A.; Andrianov A.K.; Toth E.A.; Foung S.K.H.; Pierce B.G.; Fuerst T.R. 收藏  |  浏览/下载:47/0  |  提交时间:2021/05/24 |
| CRISPR-engineered T cells in patients with refractory cancer 期刊论文 , 2020, 卷号: 367, 期号: 6481 作者: Stadtmauer E.A.; Fraietta J.A.; Davis M.M.; Cohen A.D.; Weber K.L.; Lancaster E.; Mangan P.A.; Kulikovskaya I.; Gupta M.; Chen F.; Tian L.; Gonzalez V.E.; Xu J.; Jung I.-Y.; Joseph Melenhorst J.; Plesa G.; Shea J.; Matlawski T.; Cervini A.; Gaymon A.L.; Desjardins S.; Lamontagne A.; Salas-Mckee J.; Fesnak A.; Siegel D.L.; Levine B.L.; Jadlowsky J.K.; Young R.M.; Chew A.; Hwang W.-T.; Hexner E.O.; Carreno B.M.; Nobles C.L.; Bushman F.D.; Parker K.R.; Qi Y.; Satpathy A.T.; Chang H.Y.; Zhao Y.; Lacey S.F.; June C.H. 收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28 heterodimer programmed death 1 receptor T lymphocyte receptor alpha chain T lymphocyte receptor beta chain cancer cell gene gene expression genetic engineering immunity protein adult aged Article cancer patient cell engineering chromosome translocation clinical article clustered regularly interspaced short palindromic repeat controlled study CRISPR-CAS9 system feasibility study female gene editing gene expression gene frequency gene locus genetic code human human cell male middle aged myeloma PDCD1 gene phase 1 clinical trial priority journal sarcoma T lymphocyte TRAC gene TRBC gene tumor immunity |
| Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2 期刊论文 , 2020, 卷号: 367, 期号: 6485 作者: Yan R.; Zhang Y.; Li Y.; Xia L.; Guo Y.; Zhou Q. 收藏  |  浏览/下载:17/0  |  提交时间:2020/07/28 angiotensin converting enzyme 2 coronavirus spike glycoprotein heterodimer homodimer amino acid transporter angiotensin converting enzyme 2 dipeptidyl carboxypeptidase protein binding SLC6A19 protein, human spike protein, SARS-CoV-2 virus receptor enzyme gene gene expression protein ultrastructure virus Article binding site complex formation controlled study coronavirus disease 2019 cryoelectron microscopy dimerization embryo enzyme structure human human cell nonhuman priority journal protein domain SARS-related coronavirus Severe acute respiratory syndrome coronavirus 2 amino acid sequence Betacoronavirus Coronavirus infection molecular model pandemic protein multimerization SARS coronavirus sequence alignment ultrastructure virus pneumonia Coronavirus SARS coronavirus Amino Acid Sequence Amino Acid Transport Systems, Neutral Betacoronavirus Coronavirus Infections Cryoelectron Microscopy Humans Models, Molecular Pandemics Peptidyl-Dipeptidase A Pneumonia, Viral Protein Binding Protein Domains Protein Multimerization Receptors, Virus SARS Virus Sequence Alignment Spike Glycoprotein, Coronavirus |
| De novo design of tunable, pH-driven conformational changes 期刊论文 Science, 2019, 卷号: 364, 期号: 6442 作者: Boyken S.E.; Benhaim M.A.; Busch F.; Jia M.; Bick M.J.; Choi H.; Klima J.C.; Chen Z.; Walkey C.; Mileant A.; Sahasrabuddhe A.; Wei K.Y.; Hodge E.A.; Byron S.; Quijano-Rubio A.; Sankaran B.; King N.P.; Lippincott-Schwartz J.; Wysocki V.H.; Lee K.K.; Baker D. 收藏  |  浏览/下载:30/0  |  提交时间:2022/01/14 |