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Real-time observation of cas9 postcatalytic domain motions 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2
作者:  Wang Y.;  Mallon J.;  Wang H.;  Singh D.;  Jo M.H.;  Hua B.;  Bailey S.;  Ha T.
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
Very fast CRISPR on demand 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Liu Y.;  Zou R.S.;  He S.;  Nihongaki Y.;  Li X.;  Razavi S.;  Wu B.;  Ha T.
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/28
Cas9 endonuclease Streptococcus pyogenes  double strand break repair protein MRE11  H2AX protein, human  histone  MRE11 protein, human  CRISPR Cas system  DNA cleavage  DNA repair  double stranded DNA break  fluorescence imaging  gene editing  genetics  HEK293 cell line  human  light  metabolism  phosphorylation  procedures  radiation response  single cell analysis  CRISPR-Associated Protein 9  CRISPR-Cas Systems  DNA Breaks, Double-Stranded  DNA Cleavage  DNA Repair  Gene Editing  HEK293 Cells  Histones  Humans  Light  MRE11 Homologue Protein  Optical Imaging  Phosphorylation  Single-Cell Analysis