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The body's dangerous defenders 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Leslie M.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
alvelestat  avacopan  chemokine receptor CXCR2  danirixin  leukocyte elastase  n [2 (2,3 difluorobenzylthio) 6 (2,3 dihydroxy 1 methylpropoxy) 4 pyrimidinyl] 1 azetidinesulfonamide  nemiralisib  simvastatin  leukocyte elastase inhibitor  antimicrobial activity  apoptosis  cell  enzyme activity  physiological response  ANCA associated vasculitis  Article  autoimmune disease  autoimmunity  bacterial pneumonia  bactericidal activity  bronchiolitis obliterans  drug targeting  extracellular matrix  extracellular trap  hematopoietic stem cell transplantation  human  immunity  immunocompetent cell  infection  inflammation  lung disease  neutrophil  neutrophil chemotaxis  nonhuman  priority journal  risk factor  sepsis  single cell RNA seq  autoimmune disease  chronic obstructive lung disease  clinical trial (topic)  drug effect  enzymology  immunology  lung tumor  neutrophil  Autoimmune Diseases  Clinical Trials as Topic  Humans  Lung Neoplasms  Neutrophils  Proteinase Inhibitory Proteins, Secretory  Pulmonary Disease, Chronic Obstructive  
The evolutionary dynamics and fitness landscape of clonal hematopoiesis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Watson C.J.;  Papula A.L.;  Poon G.Y.P.;  Wong W.H.;  Young A.L.;  Druley T.E.;  Fisher D.S.;  Blundell J.R.
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/28
DNA methyltransferase 3A  blood  cancer  evolutionary biology  fitness  gene expression  genetic drift  hematology  mutation  pathogenicity  acute myeloid leukemia  age distribution  allele  Article  cancer risk  cell expansion  cell population  clonal hematopoiesis  epigenetics  gene mutation  genetic variability  hematological parameters  hematopoiesis  hematopoietic stem cell  human  molecular evolution  mutational analysis  nonhuman  priority journal  single nucleotide polymorphism  somatic mutation  stem cell self-renewal  
Hope for hematological diseases 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Wilkinson A.C.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
fibronectin  polyvinyl alcohol  serum albumin  stem cell factor  thrombopoietin  blood  disease incidence  disease treatment  laboratory method  medicine  public health  Article  cell differentiation  cell self-renewal  chemotherapy  CRISPR-CAS9 system  ex vivo study  gene editing  gene therapy  genotoxicity  graft versus host reaction  hematologic disease  hematopoiesis  hematopoietic stem cell transplantation  human  morbidity  mortality  multipotent stem cell  nonhuman  priority journal  radiotherapy  stem cell culture  stem cell expansion